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. 2022 Dec 1;9:995103. doi: 10.3389/fmed.2022.995103

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Copyright © 2022 Xiao, Xiao and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROC curves of the 10 hub genes in identifying renal involvement patients with high disease activity (SLEDAI > 15). (A,B) ROC curves of the 10 hub genes. (C) ROC curve of the combination model of the 10 hub genes. The combination model was 14.6627 + –0.3795 * DEFA4 + 0.2401 * CTSG + –0.0942 * RETN + –0.0114 * CEACAM8 + –0.2822 * TOP2A + 0.5422 * LTF + 0.1112 * MPO + –0.1143 * ELANE + –0.8064 * BIRC5 + –1.0725 * LCN2. The AUC of the combination model was 0.846 and the 95% confidence interval (CI) was 0.762-0.930.