TABLE 7.
Key transcriptional factors (TFs) of hub genes.
| Key TF | Description | P-value | List of overlapped genes |
| CEBPE | CCAAT/Enhancer binding protein (C/EBP), epsilon | 5.30E-06 | LTF, CTSG |
| SP1 | Sp1 transcription factor | 7.20E-05 | MPO, BIRC5, RETN, LTF |
| LEF1 | Lymphoid enhancer-binding factor 1 | 0.000102 | BIRC5, ELANE |
| MYB | V-myb myeloblastosis viral oncogene homolog (avian) | 0.000167 | ELANE, CTSG |
| RUNX1 | Runt-related transcription factor 1 | 0.000195 | MPO, ELANE |
| SPI1 | Spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.00047 | ELANE, CTSG |
| E2F1 | E2F transcription factor 1 | 0.00217 | BIRC5, TOP2A |
| RELA | V-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.0105 | BIRC5, LCN2 |
| NFKB1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0106 | LCN2, BIRC5 |