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. 2022 Dec 15;17(12):e0279041. doi: 10.1371/journal.pone.0279041

Fig 3. Dams exposed to acute HFHS feeding are insulin resistant.

Fig 3

(A) Experimental timeline for hyperinsulinemic euglycemic clamp studies. (B) Average glucose infusion rate is significantly decreased in P HFHS dams compared to control dams as well as NP CD and NP HFHS females. (C) Glucose infusion rate over time is significantly reduced in P HFHS dams compared to all other groups, P CD and NP HFHS glucose infusion rates over time are significantly decreased compared to NP CD, but not different from each other. N = 5 NP CD, 7 P CD, 5 NP HFHS and 7 P HFHS mice. Difference subscripts represent differences among groups (p<0.01), *p<0.01; **p<0.01; Lines represent median values.