Table 3. Top 60 SNPs that reached P < 1×10−5 from bivariate GWAS of grip strength and depression.
| SNP | Chr | Band | BP | P-value | Gene/Nearest gene |
|---|---|---|---|---|---|
| rs118190698 | 18 | q21.2 | 52480259 | 1.35E-09 | RAB27B |
| rs79530590 | 18 | q21.2 | 48520209 | 1.50E-09 | LOC107985152 |
| rs117744620 | 14 | q21.3 | 50079611 | 3.31E-09 | LRR1 |
| rs117546604 | 18 | q21.2 | 48472778 | 3.84E-09 | ME2 |
| rs150220336 | 18 | q21.2 | 48388016 | 4.39E-08 | ME2 |
| rs147079354 | 18 | q21.2 | 48447754 | 4.62E-08 | ME2 |
| rs79287957 | 20 | p12.2 | 11048805 | 4.92E-08 | LINC02871 |
| rs75534602 | 7 | p12.1 | 50634883 | 6.13E-08 | DDC |
| rs117533783 | 7 | p12.2 | 50525408 | 7.82E-08 | DDC |
| rs116994552 | 8 | p21.1 | 28076758 | 8.16E-08 | LOC100131127 |
| rs11973477 | 7 | q32.3 | 130908819 | 1.01E-07 | MKLN1 |
| rs6961574 | 7 | q32.3 | 130908776 | 1.04E-07 | MKLN1 |
| rs149538842 | 3 | p12.3 | 76440134 | 1.06E-07 | ROBO2 |
| rs78161270 | 7 | p12.2 | 50541930 | 1.13E-07 | DDC |
| rs117549429 | 21 | q22.13 | 38971496 | 1.53E-07 | KCNJ6 |
| rs74214322 | 7 | p13 | 45401720 | 3.00E-07 | ELK1P1 |
| rs118025410 | 5 | q13.2 | 68859027 | 3.08E-07 | GTF2H2C |
| rs76553625 | 5 | q12.3 | 64268965 | 3.19E-07 | CWC27 |
| rs5773363 | 1 | p35.2 | 31918631 | 3.24E-07 | SERINC2 |
| rs12657552 | 5 | p13 | 68855113 | 3.29E-07 | GTF2H2C |
| rs4081993 | 5 | p13 | 68856116 | 3.33E-07 | GTF2H2C |
| rs147869550 | 15 | q23 | 71596350 | 4.45E-07 | THSD4 |
| rs1868887 | 7 | p12.2 | 50479856 | 4.76E-07 | IKZF1 |
| rs79147986 | 5 | p15.1 | 15593286 | 5.05E-07 | FBXL7 |
| rs201380943 | 11 | p11.2 | 47778625 | 5.41E-07 | FNBP4 |
| rs116890548 | 12 | q24.31 | 121620387 | 5.43E-07 | P2RX7 |
| rs573505577 | 11 | p15.1 | 19918670 | 5.48E-07 | NAV2 |
| rs80251137 | 7 | q36.3 | 155920157 | 6.09E-07 | LOC105375601 |
| rs2995920 | 4 | p14.3 | 37904456 | 6.24E-07 | TBC1D1 |
| rs141475535 | 1 | q44 | 244427543 | 7.24E-07 | LOC105373262 |
| rs116961485 | 8 | q13.1 | 66227114 | 7.79E-07 | PPIAP86 |
| rs534143679 | 3 | p22.3 | 32433754 | 7.96E-07 | CMTM7 |
| rs62358249 | 5 | q14.3 | 84421657 | 8.02E-07 | RBBP4P6 |
| rs17008263 | 1 | q41 | 220877255 | 8.02E-07 | C1orf115 |
| rs11851625 | 14 | q12 | 30314159 | 8.15E-07 | PRKD1 |
| rs12563371 | 1 | p21.1 | 103499755 | 8.22E-07 | COL11A1 |
| rs200867673 | 7 | p14.3 | 32871494 | 8.88E-07 | DPY19L1P2 |
| rs2297807 | 20 | q13.33 | 62575853 | 8.90E-07 | UCKL1 |
| rs57042988 | 7 | q31.2 | 114791544 | 9.16E-07 | LINC01392 |
| rs10914394 | 1 | p35.2 | 31915692 | 9.18E-07 | LOC105378625 |
| rs181979988 | 4 | p14.3 | 38496704 | 9.38E-07 | LINC01258 |
| rs141325897 | 1 | p21.1 | 103598274 | 9.38E-07 | COL11A1 |
| rs57244134 | 12 | q22.13 | 94661218 | 9.93E-07 | CEP83 |
| rs10914386 | 1 | p35.2 | 31909072 | 1.06E-06 | SERINC2 |
| rs10914387 | 1 | p35.2 | 31909124 | 1.06E-06 | SERINC2 |
| rs6702129 | 1 | p35.2 | 31910482 | 1.06E-06 | SERINC2 |
| rs1320586 | 1 | p35.2 | 31908201 | 1.07E-06 | SERINC2 |
| rs12122438 | 1 | p35.2 | 31909448 | 1.07E-06 | SERINC2 |
| rs12141959 | 1 | p35.2 | 31909380 | 1.07E-06 | SERINC2 |
| rs6690908 | 1 | p35.2 | 31910089 | 1.07E-06 | SERINC2 |
| rs6675883 | 1 | p35.2 | 31910202 | 1.07E-06 | SERINC2 |
| rs6688664 | 1 | p35.2 | 31910337 | 1.07E-06 | SERINC2 |
| rs139995350 | 1 | p35.2 | 31910430 | 1.07E-06 | SERINC2 |
| rs6691338 | 1 | p35.2 | 31910655 | 1.07E-06 | SERINC2 |
| rs75429043 | 14 | q12 | 30316306 | 1.13E-06 | PRKD1 |
| rs11795332 | 9 | p22.3 | 15352410 | 1.13E-06 | RPL7P33 |
| rs113400337 | 9 | p22.3 | 15360062 | 1.13E-06 | RPL7P33 |
| rs377290438 | 6 | q12 | 68889736 | 1.14E-06 | LINC02549 |
| rs12323862 | 14 | q12 | 30317951 | 1.14E-06 | PRKD1 |
| rs79219406 | 9 | p22.3 | 15347617 | 1.18E-06 | RPL7P33 |
SNP, nucleotide polymorphism; Chr, chromosome; BP, base pair.