Table 5.
TST conversion*(N = 50) | Baseline IGRA+ (N = 23) median (IQR) | Baseline IGRA- (N = 27) median (IQR) | ||||
---|---|---|---|---|---|---|
Baseline | 3-month follow-up | p | Baseline | 3-month follow-up | p | |
TST induration, mm | 0.00 (0.00–0.00) | 13.50 (11.00–20.00) | < 0.001 | 0.00 (0.00–0.00) | 13.50 (11.50–16.00) | < 0.001 |
IGRA TB1-Nil, IU/ml | 0.85 (0.49–1.44) | 1.33 (0.43–3.70) | 0.020 | 0.01 (0.00–0.08) | 0.01 (0.00–0.20) | 0.024 |
IGRA TB2-Nil, IU/ml | 0.81 (0.51–1.46) | 1.43 (0.73–3.49) | 0.017 | 0.02 (0.00–0.08) | 0.03 (0.00–0.22) | 0.004 |
C-TST conversion& (N = 26) | Baseline IGRA+ (N = 17) median (IQR) | Baseline IGRA– (N = 9) median (IQR) | ||||
Baseline | 3–month follow–up | p | Baseline | 3–month follow–up | p | |
C-TST induration/ erythema, mm | 0.00 (0.00–0.00) | 20.00 (17.50–23.00) | < 0.001 | 0.00 (0.00–0.00) | 18.00 (10.00–24.00) | 0.004 |
IGRA TB1-Nil, IU/ml | 0.68 (0.49–2.01) | 1.45 (0.97–2.51) | 0.132 | 0.04 (0.01–0.09) | 0.43 (0.08–0.76) | 0.016 |
IGRA TB2-Nil, IU/ml | 0.72 (0.55–1.78) | 1.45 (0.86–2.28) | 0.109 | 0.02 (0.01–0.08) | 0.62 (0.06–0.72) | 0.016 |
C-TST, Creation tuberculin skin test; IGRA, Interferon-gamma release assay; IQR, Interquartile range; TST, Tuberculin skin test; The differences were tested by Wilcoxon matched-pairs signed-rank test.
TST conversion was defined as the average diameter of induration ≥10 mm for those with baseline survey < 5 mm, or increased ≥ 10 mm when the baseline survey result was between 5 and 10 mm.
C-TST conversion was defined as the average diameter of induration and erythema increased from < 5mm at baseline survey to induration or erythema ≥ 5mm at follow-up survey.