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. 2022 Dec 1;10:1025550. doi: 10.3389/fpubh.2022.1025550

Table 5.

Quantitative results of TST, C-TST and IGRA in skin testing converted subjects.

TST conversion*(N = 50) Baseline IGRA+ (N = 23) median (IQR) Baseline IGRA- (N = 27) median (IQR)
Baseline 3-month follow-up p Baseline 3-month follow-up p
TST induration, mm 0.00 (0.00–0.00) 13.50 (11.00–20.00) < 0.001 0.00 (0.00–0.00) 13.50 (11.50–16.00) < 0.001
IGRA TB1-Nil, IU/ml 0.85 (0.49–1.44) 1.33 (0.43–3.70) 0.020 0.01 (0.00–0.08) 0.01 (0.00–0.20) 0.024
IGRA TB2-Nil, IU/ml 0.81 (0.51–1.46) 1.43 (0.73–3.49) 0.017 0.02 (0.00–0.08) 0.03 (0.00–0.22) 0.004
C-TST conversion& (N = 26) Baseline IGRA+ (N = 17) median (IQR) Baseline IGRA– (N = 9) median (IQR)
Baseline 3–month follow–up p Baseline 3–month follow–up p
C-TST induration/ erythema, mm 0.00 (0.00–0.00) 20.00 (17.50–23.00) < 0.001 0.00 (0.00–0.00) 18.00 (10.00–24.00) 0.004
IGRA TB1-Nil, IU/ml 0.68 (0.49–2.01) 1.45 (0.97–2.51) 0.132 0.04 (0.01–0.09) 0.43 (0.08–0.76) 0.016
IGRA TB2-Nil, IU/ml 0.72 (0.55–1.78) 1.45 (0.86–2.28) 0.109 0.02 (0.01–0.08) 0.62 (0.06–0.72) 0.016

C-TST, Creation tuberculin skin test; IGRA, Interferon-gamma release assay; IQR, Interquartile range; TST, Tuberculin skin test; The differences were tested by Wilcoxon matched-pairs signed-rank test.

*

TST conversion was defined as the average diameter of induration ≥10 mm for those with baseline survey < 5 mm, or increased ≥ 10 mm when the baseline survey result was between 5 and 10 mm.

&

C-TST conversion was defined as the average diameter of induration and erythema increased from < 5mm at baseline survey to induration or erythema ≥ 5mm at follow-up survey.