FIG. 6.

Responses of 987P fimbria-specific serum IgG and IgA (A) and mucosal IgA in stools (B). BALB/c mice were immunized orally with two doses of serovar Typhimurium CS3263/pCS114 in a 26-day interval. Sera were collected before and at 6 to 8 weeks after the first immunization. Serum IgG (solid bars) and IgA (hatched bars) were measured individually. Error bars represent the standard deviations of the values for seven mice. The IgA levels in stools were measured from the pooled fecal pellets. No antibodies were detected in fecal pellets from preimmunized mice.