Table 2. List of the differentially expressed genes among Timd4+ thymic macrophages, Cx3cr1+ thymic macrophages, and thymic monocytes.
The top 100 differentially expressed genes among the three clusters are listed by their negative log10 transformed p-value.
| Cx3cr1 + ThyMacs | Timd4 + ThyMacs | ThyMonos | |||
|---|---|---|---|---|---|
| Gene name | Adjusted p-value | Gene name | Adjusted p-value | Gene name | Adjusted p-value |
| Ctsz | 0 | Hpgd | 0 | Alox5ap | 0 |
| Cd63 | 0 | Serpinb6a | 0 | S100a6 | 0 |
| Pmepa1 | 0 | Slc40a1 | 0 | Ly6c2 | 0 |
| Zmynd15 | 0 | Cd81 | 0 | Ifi27l2a | 0 |
| Olfml3 | 0 | Vcam1 | 0 | Fau | 0 |
| Mmp2 | 0 | Cfp | 0 | Coro1a | 0 |
| AU020206 | 1.60E-290 | Spic | 0 | Ccr2 | 0 |
| Plxnd1 | 1.59E-285 | Trf | 0 | Rps27 | 0 |
| Cst7 | 8.68E-279 | Actn1 | 0 | Tmsb10 | 0 |
| Dnase1l3 | 2.45E-270 | Maf | 0 | Ifitm2 | 7.21E-302 |
| Timp2 | 2.15E-267 | Pld3 | 0 | Fxyd5 | 6.36E-299 |
| Lgals3bp | 8.69E-263 | Il18 | 0 | Rps19 | 2.04E-292 |
| Pdgfa | 6.87E-255 | Mrc1 | 0 | Rpl18 | 6.50E-291 |
| Mmp14 | 2.33E-253 | Crip2 | 0 | Rpl9 | 1.11E-289 |
| Fam46c | 9.99E-235 | Tmem65 | 0 | Rps23 | 1.28E-289 |
| Chst2 | 1.19E-226 | Igf1 | 0 | Napsa | 8.91E-279 |
| Cp | 5.36E-225 | Epb41l3 | 0 | Ms4a4c | 8.25E-272 |
| Camk1 | 7.12E-225 | Timd4 | 0 | Plac8 | 2.10E-270 |
| B2m | 1.09E-222 | Blvrb | 0 | Rpl18a | 9.26E-269 |
| Lhfpl2 | 4.52E-217 | Clec1b | 0 | S100a4 | 4.98E-268 |
| Acp5 | 5.90E-216 | Cd68 | 0 | Cd52 | 3.67E-267 |
| Lag3 | 3.91E-213 | Axl | 0 | Rps14 | 1.94E-266 |
| Lyz2 | 1.28E-209 | Paqr9 | 3.32E-307 | Ifitm3 | 3.19E-263 |
| H2-M2 | 1.22E-199 | Sdc3 | 3.45E-305 | Rpl34 | 2.02E-261 |
| Psap | 7.26E-198 | Myo9a | 5.59E-305 | Rps27a | 3.67E-260 |
| Gatm | 1.33E-192 | Scp2 | 3.79E-302 | Rpl36 | 1.54E-259 |
| Cpd | 1.50E-192 | Selenop | 2.10E-295 | Rps16 | 2.55E-258 |
| C3 | 2.34E-187 | Lrp1 | 2.08E-294 | Rpl24 | 1.37E-257 |
| Cxcl16 | 8.11E-183 | Lap3 | 1.45E-290 | Rps9 | 6.34E-253 |
| Lgals3 | 1.57E-182 | Marcks | 2.77E-279 | Gpr141 | 1.21E-246 |
| Ube2j1 | 1.63E-180 | Glul | 3.64E-279 | Rpl27a | 3.06E-243 |
| Plxnc1 | 9.84E-180 | Hebp1 | 3.76E-278 | Rpl17 | 8.15E-241 |
| Stab1 | 4.07E-176 | Ear2 | 4.53E-276 | Rps24 | 1.46E-240 |
| Cyth1 | 3.27E-163 | Apoc1 | 2.49E-275 | Rps13 | 2.34E-236 |
| Spsb1 | 3.96E-163 | Kcna2 | 3.72E-275 | Rpl38 | 1.95E-226 |
| Blnk | 2.35E-162 | Myo10 | 9.05E-269 | H2-DMb1 | 1.02E-223 |
| Cx3cr1 | 9.29E-162 | Atp13a2 | 2.95E-267 | Rps18 | 5.39E-223 |
| Med10 | 5.25E-161 | Slc1a3 | 6.24E-263 | Rpl19 | 3.68E-221 |
| Nek6 | 5.28E-160 | Slco2b1 | 1.11E-258 | Rpl8 | 2.01E-219 |
| Ptms | 1.05E-159 | mt-Nd2 | 3.45E-258 | Rpl7a | 4.17E-217 |
| Anxa5 | 1.10E-156 | Wwp1 | 2.16E-253 | Gm34084 | 5.23E-216 |
| Gpnmb | 1.21E-154 | Aplp2 | 4.22E-248 | Rpl13 | 2.08E-215 |
| Itgb5 | 2.78E-154 | Atp8a1 | 5.03E-248 | Rpl11 | 2.47E-213 |
| Myo5a | 1.11E-146 | P2ry13 | 3.17E-247 | Rpl35a | 2.13E-210 |
| Runx3 | 1.81E-146 | Ccdc148 | 4.70E-245 | Rpsa | 1.62E-209 |
| Tmem176a | 2.34E-144 | Grn | 1.58E-244 | Rpl6 | 5.70E-208 |
| Ctss | 4.81E-141 | Bank1 | 1.82E-239 | Tpt1 | 2.63E-206 |
| Sh3pxd2b | 9.38E-141 | Mertk | 2.15E-238 | Rack1 | 2.14E-203 |
| Rtcb | 4.42E-140 | Nr1h3 | 1.13E-235 | Rpl23 | 6.14E-199 |
| Fam20c | 1.91E-139 | Prnp | 2.93E-235 | Rpl26 | 7.48E-198 |
| Il2rg | 8.84E-138 | Ninj1 | 2.42E-234 | Rps6 | 6.64E-197 |
| Lpcat2 | 8.53E-137 | Fcna | 3.33E-233 | Rps10 | 2.06E-195 |
| Kynu | 8.49E-136 | Csrp1 | 1.16E-230 | Ier5 | 1.06E-191 |
| Tnfsf13b | 8.77E-136 | Rgl1 | 7.18E-229 | Rps3 | 8.23E-185 |
| Gpr157 | 1.18E-135 | Lpl | 4.94E-223 | Rpl27 | 8.23E-185 |
| Tgfbr1 | 7.63E-135 | Fam213b | 1.08E-222 | Rps5 | 8.36E-185 |
| H2-K1 | 1.15E-133 | Tcf7l2 | 1.26E-222 | Rps7 | 3.96E-182 |
| Basp1 | 1.23E-133 | AB124611 | 4.64E-221 | Rps15a | 6.82E-182 |
| Pla2g7 | 1.80E-132 | Abcc3 | 3.28E-216 | Rps11 | 1.97E-180 |
| Fth1 | 4.19E-131 | Fcgrt | 5.79E-216 | Rps4x | 5.07E-180 |
| Ggh | 1.85E-126 | Tgm2 | 1.88E-215 | Rplp0 | 3.09E-177 |
| Adam19 | 6.94E-126 | Itgad | 5.35E-214 | Ly6i | 8.17E-176 |
| C3ar1 | 7.35E-125 | Ptgs1 | 2.94E-213 | S100a11 | 6.23E-175 |
| Ccl12 | 3.37E-123 | Laptm4a | 1.01E-212 | Atox1 | 1.22E-174 |
| Hvcn1 | 2.51E-121 | Comt | 1.33E-206 | Pim1 | 9.56E-174 |
| Anxa3 | 8.60E-121 | Creg1 | 3.24E-205 | Sh3bgrl3 | 3.97E-173 |
| Tgfbi | 1.88E-120 | Adgre1 | 9.67E-205 | Ciita | 7.35E-173 |
| Ctsd | 2.73E-117 | Clec12a | 6.33E-204 | Eef1a1 | 6.09E-172 |
| Itm2c | 5.19E-116 | Tspan4 | 7.80E-203 | Rps3a1 | 9.09E-168 |
| Tmem119 | 5.62E-116 | Txn1 | 9.13E-203 | Gm2a | 6.07E-165 |
| Rap2a | 1.03E-114 | Ctsb | 9.52E-201 | Ptprc | 2.05E-163 |
| Ctsl | 4.00E-114 | Mrap | 5.65E-197 | Rpl37 | 1.51E-161 |
| Itga6 | 1.83E-113 | Slc16a9 | 5.99E-197 | Rps25 | 3.03E-160 |
| B4galnt1 | 2.45E-113 | Abcg3 | 3.83E-196 | H3f3a | 5.92E-159 |
| Fam3c | 1.64E-112 | Pla2g15 | 4.22E-196 | Btg2 | 1.14E-158 |
| Tmem173 | 1.54E-111 | C1qc | 6.17E-192 | Rpl15 | 1.42E-158 |
| Ski | 3.59E-111 | Agpat3 | 1.68E-191 | Cnn2 | 1.09E-156 |
| Anpep | 5.85E-111 | Hs6st1 | 1.95E-191 | Cdkn1a | 2.57E-156 |
| Gng2 | 2.37E-110 | Dmpk | 2.15E-191 | Slfn1 | 4.83E-155 |
| Nceh1 | 2.88E-110 | Cd38 | 1.79E-190 | Sem1 | 4.08E-154 |
| H2-Q7 | 4.94E-108 | Tmem26 | 2.02E-189 | Lsp1 | 1.34E-152 |
| Rtn1 | 1.28E-106 | Slc11a1 | 1.05E-188 | Rpl37a | 1.78E-152 |
| Sorl1 | 1.31E-103 | Cd300a | 1.41E-187 | Rpl22 | 3.64E-152 |
| Glipr1 | 1.22E-102 | Slc7a7 | 3.28E-187 | Sirpb1c | 4.81E-152 |
| Gsn | 2.00E-102 | Cyb5a | 6.94E-187 | Traf1 | 6.97E-152 |
| Afdn | 4.54E-102 | Sipa1l1 | 7.41E-187 | Emb | 4.22E-151 |
| Ak2 | 1.11E-101 | Il18bp | 1.48E-186 | Rpl30 | 1.32E-147 |
| Ntpcr | 2.21E-98 | Cd86 | 2.52E-183 | Rps15 | 1.14E-146 |
| Scarb2 | 3.16E-97 | Vamp5 | 3.05E-183 | H2-Ab1 | 2.84E-145 |
| Creb5 | 5.41E-97 | Jup | 6.69E-182 | Il1b | 3.05E-145 |
| Gsto1 | 5.56E-97 | Blvra | 1.30E-178 | Rps28 | 4.52E-145 |
| Ncf1 | 4.26E-96 | Mgst1 | 6.48E-178 | Jarid2 | 1.82E-143 |
| Ppfia4 | 4.97E-96 | Tbxas1 | 1.47E-177 | Rps26 | 1.53E-142 |
| Chchd10 | 7.77E-96 | Hpgds | 2.04E-177 | Rpl32 | 4.21E-142 |
| Gna12 | 1.23E-95 | Tgfbr2 | 2.70E-176 | Pld4 | 9.07E-142 |
| Mvb12b | 1.80E-95 | Clec4n | 3.52E-175 | Cbfa2t3 | 1.54E-141 |
| Rasal3 | 1.45E-94 | Ms4a7 | 5.30E-175 | Rps21 | 4.04E-141 |
| Scoc | 6.86E-94 | Sirpa | 3.35E-171 | Fgr | 4.04E-141 |
| Cfb | 6.00E-93 | Fyn | 2.84E-168 | Rps8 | 1.11E-139 |
| Lmna | 1.04E-92 | Cadm1 | 2.20E-167 | Cd74 | 5.34E-138 |