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Somatic mutations in patients with LGSC.
| Subject | Pathogenic somatic mutations | Somatic VUS |
|---|---|---|
| 1 |
BRCA1 (exon23: c.5497G>A p.Val1833Met) NRAS (exon3: c.182A>G p.Gln61Arg) |
– |
| 2 | – | – |
| 3 | – |
ROS1 (c.1816_1824del: p.Gln606_Trp608del chr6: 117709132_117709141delinsT (hg19) rs748934319) KDR (c.475G>A: p.Val159Met chr4: 55981462C>T (hg19) rs545112274) |
| 4 | TP53 (exon8: c.818G>A: p.Arg273His) | ROS1 (exon12: c.1611A>G p.Ile537Met) |
| 5 | - | - |
| 6 | - | - |
| 7 | - | - |
