Table 2.
Comparison of demographic and clinical data between RSV and HMPV-positive cases
| Categories | RSV-positivea (N = 1300) | HMPV-positivea (N = 222) | P value | |
|---|---|---|---|---|
| Sex (male) | 661 (50.8%) | 106 (47.7%) | ns | |
| Age group | 0–6 m | 481 (37.4%) | 49 (22.1%) | < 0.001 |
| 6 m–3 y | 278 (21.6%) | 46 (20.7%) | ||
| 3 y–16 y | 104 (8.1%) | 22 (9.9%) | ||
| 16 y–65 y | 148 (11.5%) | 37 (16.6%) | ||
| 65 y–80 y | 127 (9.9%) | 26 (11.7%) | ||
| > 80 y | 148 (11.5%) | 42 (18.9%) | ||
| Median age in years (range) | 1.25 (0.02–98.6) | 9.3 (0.06–97.4) | < 0.001 | |
| Pediatric cases (< 16 y) | 864/1286 (67.2%) | 117/222 (52.7%) | < 0.001 | |
| Older adults (> 65 y) | 275/1286 (21.4%) | 68/222 (30.6%) | 0.0026 | |
| Ct value b | 26.0 ± 6.6 (n = 868) | 27.9 ± 5.4 (n = 166) | 0.001 | |
| Co-infectionsc | 278/1114 (25.0%) | 47/211 (22.3%) | ns | |
| Hospitalized | 1124/1256 (89.5%) | 172/195 (88.2%) | ns | |
| Intensive care | 101/1027 (9.8%) | 17/150 (11.3%) | ns | |
| Diagnosis | Bronchiolitis | 347/742 (46.8%) | 27/113 (23.9%) | < 0.001 |
| Bronchopneumonia | 94/742 (12.7%) | 31/113 (27.4%) | ||
| Influenza-like illness | 85/742 (11.4%) | 3/113 (2.6%) | ||
| Other acute respiratory diagnoses | 137/742 (18.5%) | 40/113 (35.4%) | ||
| Other diagnoses | 79 /742 (10.6%) | 12/113 (10.6%) | ||
| Fever (T > 37.5 °C) | 404/660 (61.2%) | 77/124 (62.1%) | ns | |
| Cough | 443/612 (72.4%) | 92/115 (80.0%) | ns | |
| Productive cough | 206/443 (46.5%) | 55/92 (59.8%) | 0.009 | |
| SaO2 in room air | > 95% | 235/568 (41.4%) | 36/113 (31.9%) | 0.058 |
| 95–90% | 227/568 (40.0%) | 46/113 (40.7%) | ||
| < 90% | 106/568 (18.6%) | 31/112 (27.4%) | ||
| Dyspnea | 425/602 (70.6%) | 77/112 (68.7%) | ns | |
| Antibiotic therapy | 358/613 (58.4%) | 81/114 (71.1%) | 0.012 | |
RSV respiratory syncytial virus, HMPV human metapneumovirus
aThe number of cases in which information was available is indicated at the denominator
bDiagnostic test cycle threshold (Ct) value is reported as mean ± standard deviation
cCases of RSV and HMPV co-infections were not included