. 2022 May 18;2(4):100171. doi: 10.1016/j.xops.2022.100171

Table 2.

Top 8 Radiomic Features Identified within Each OCT of the Compartments to Distinguish Super Responders and Non–super Responders to Anti–VEGF Therapy in nAMD

Features	Feature Family	Descriptor	Statistics	Subcompartment	P Value
F_f	Laws energy	L5R5L5	Median	Fluid	<0.001
	Laws energy	R5W5S5	Median	Fluid	<0.001
	Laws energy	L3E3L3	Skewness	Fluid	<0.001
	Laws energy	R5R5S5	Median	Fluid	<0.001
	Laws energy	E5L5W5	Median	Fluid	<0.001
	Laws energy	S5S5W5	Skewness	Fluid	<0.001
	Laws energy	W5E5S5	Skewness	Fluid	<0.001
	Laws energy	E5W5W5	Skewness	Fluid	<0.001
F_shrm	Laws energy	L3S3L3	Median	SHRM	<0.001
	Gabor	XY – θ = Π/4, XZ – θ = Π/2, f = 2	Median	SHRM	<0.001
	Laws energy	E5E5E5	Kurtosis	SHRM	<0.001
	Laws energy	S5W5L5	Kurtosis	SHRM	<0.001
	Laws energy	R5S5E5	Skewness	SHRM	0.001
	Gabor	XY – θ = Π/2, XZ – θ = 0, f = 2	Skewness	SHRM	<0.001
	Gabor	XY – θ = Π/4, XZ – θ = Π/4, f = 4	Skewness	SHRM	<0.001
	Gabor	XY – θ = Π/3, XZ – θ = 0, f = 2	Median	SHRM	0.001
F_rtc1	Laws energy	E3L3E3	Skewness	ILM-RPE	<0.001
	Laws energy	L3E3L3	Median	ILM-RPE	<0.001
	Laws energy	E3L3L3	Median	ILM-RPE	<0.001
	Laws energy	E3E3E3	Skewness	ILM-RPE	<0.001
	Laws energy	E3S3L3	Variance	ILM-RPE	0.0043
	Laws energy	E3L3E3	Median	ILM-RPE	<0.001
	Laws energy	S3E3L3	Kurtosis	ILM-RPE	0.005
	Laws energy	S3E3L3	Skewness	ILM-RPE	<0.001
F_rtc2	Laws energy	W5R5S5	Skewness	RPE-BM	<0.001
	Laws energy	S3L3E3	Median	RPE-BM	<0.001
	Laws energy	S3L3L3	Skewness	RPE-BM	<0.001
	Gabor	XY – θ = Π/2, XZ – θ = Π/2, f = 2	Median	RPE-BM	0.001
	Gabor	XY – θ = Π/2, XZ – θ = Π/4, f = 2	Median	RPE-BM	<0.001
	Gabor	XY – θ = Π/2, XZ – θ = Π/2, f = 4	Median	RPE-BM	<0.001
	Gabor	XY – θ = Π/3, XZ – θ = Π/4, f = 4	Median	RPE-BM	<0.001
	Laws energy	R5E5E5	Skewness	RPE-BM	<0.001
F_otc	Laws energy	L5R5L5	Median	Fluid	0.0015
	Laws energy	L3S3L3	Median	SHRM	0.012
	Laws energy	R5S5E5	Skewness	SHRM	0.032
	Laws energy	R5W5S5	Skewness	Fluid	0.002
	Laws energy	W5R5S5	Skewness	RPE-BM	0.002
	Laws energy	S3L3L3	Skewness	RPE-BM	0.016
	Laws energy	L3E3L3	Skewness	Fluid	0.017
	Laws energy	E5E5E5	Kurtosis	SHRM	0.014

BM = Bruch’s membrane; ILM = internal limiting membrane; RPE = retinal pigment epithelium; SHRM = subretinal hyperreflective material.