Table 2.
Prevalence of symptomatic themes by demographic categories.
| A: Theme | Full sample |
Employment status |
Education level |
Sex |
Age |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prevalence, % |
Prevalence, % |
Prevalence, % |
Prevalence, % |
Prevalence, % |
|||||||||
| All participants (N = 497) | Employed | Unable to work | p-value | College + | HS, technical, below | p-value | Male | Female | p-value | Age <63.3 | Age >63.3 | p-value | |
| Problems with your hands or fingers | 87.7 | 77.03 | 89.6 | 0.0061∗ | 86.49 | 91.34 | 0.16 | 90.94 | 82.35 | 0.007∗ | 88.41 | 87.02 | 0.68 |
| Problems with your shoulders or arms | 79.9 | 72.97 | 81.09 | 0.12 | 78.11 | 85.04 | 0.10 | 83.17 | 74.33 | 0.02 | 82.40 | 77.48 | 0.18 |
| Inability to do activities | 93.8 | 90.54 | 94.33 | 0.20 | 93.24 | 95.28 | 0.53 | 95.79 | 90.37 | 0.02 | 93.56 | 93.89 | 1 |
| Hip, thigh, or knee weakness | 80.1 | 68.92 | 82.03 | 0.0118∗ | 78.65 | 84.25 | 0.20 | 79.94 | 80.75 | 0.91 | 81.97 | 78.24 | 0.31 |
| Limitations with your mobility or walking | 86.7 | 77.03 | 88.42 | 0.01 | 85.68 | 89.76 | 0.29 | 85.11 | 89.84 | 0.17 | 85.84 | 87.40 | 0.69 |
| Decreased performance in social situations | 85.7 | 63.51 | 89.55 | <0.0001∗ | 84.51 | 88.98 | 0.24 | 85.99 | 85.03 | 0.79 | 83.69 | 87.36 | 0.25 |
| Decreased satisfaction in social situations | 81.9 | 67.57 | 84.36 | 0.0016∗ | 81.03 | 84.25 | 0.50 | 81.17 | 83.42 | 0.55 | 81.97 | 81.61 | 1 |
| Difficulty thinking | 27.7 | 20.55 | 28.92 | 0.16 | 24.86 | 35.71 | 0.02 | 29.47 | 24.86 | 0.30 | 30.70 | 25.10 | 0.19 |
| Emotional issues | 68.6 | 71.62 | 68.1 | 0.59 | 67.03 | 73.23 | 0.22 | 66.34 | 72.73 | 0.16 | 75.11 | 62.55 | 0.0035∗ |
| Impaired body image | 69.6 | 56.76 | 71.8 | 0.01 | 69.11 | 70.87 | 0.74 | 67.53 | 73.26 | 0.19 | 72.10 | 67.05 | 0.24 |
| Fatigue | 92.6 | 89.19 | 93.14 | 0.23 | 91.89 | 94.49 | 0.43 | 91.59 | 94.12 | 0.38 | 93.13 | 91.98 | 0.73 |
| Impaired sleep or daytime sleepiness | 77.9 | 73.38 | 77.78 | 1 | 75.95 | 83.46 | 0.08 | 74.76 | 82.89 | 0.03 | 82.40 | 73.66 | 0.02 |
| Pain | 55.8 | 41.89 | 58.23 | 0.0109∗ | 52.17 | 66.40 | 0.0066∗ | 55.70 | 55.68 | 1 | 58.01 | 53.85 | 0.36 |
| Gastrointestinal issues | 52.7 | 43.24 | 54.33 | 0.10 | 52.34 | 53.54 | 0.84 | 52.94 | 52.46 | 0.93 | 51.32 | 53.64 | 0.65 |
| Breathing difficulties | 58.4 | 36.99 | 62.14 | <0.0001∗ | 59.29 | 55.91 | 0.53 | 55.70 | 63.24 | 0.11 | 55.22 | 61.30 | 0.20 |
| Choking or swallowing issues | 64.0 | 32.88 | 69.36 | <0.0001∗ | 62.67 | 67.72 | 0.34 | 59.61 | 70.97 | 0.0119∗ | 59.91 | 67.31 | 0.09 |
| Communication difficulties | 63.0 | 42.47 | 66.59 | 0.0001∗ | 61.48 | 67.46 | 0.24 | 60.13 | 67.57 | 0.10 | 61.14 | 64.37 | 0.51 |
| B: Theme | Breathing status |
Speech status |
Time since first signs of weakness (months) |
Feeding tube for nutrition or hydration status |
Location of symptom onset |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prevalence, % |
Prevalence, % |
Prevalence, % |
Prevalence, % |
Prevalence, % |
|||||||||||
| Breathe with assistive ventilation | Breathe without assistive ventilation | p-value | Able to talk clearly with no changes in speech | Others | p-value | ≤34 months | >34 months | p-value | No | Yes | p-value | Limb onset | Bulbar onset | p-value | |
| Problems with your hands or fingers | 92.97 | 84.62 | 0.0068∗ | 85.63 | 88.85 | 0.32 | 82.68 | 92.98 | 0.0006∗ | 88.92 | 83.00 | 0.12 | 91.80 | 73.15 | <0.0001∗ |
| Problems with your shoulders or arms | 87.57 | 75.32 | 0.0011∗ | 81.03 | 79.26 | 0.73 | 73.62 | 86.78 | 0.0003∗ | 79.35 | 82.00 | 0.68 | 84.13 | 64.81 | <0.0001∗ |
| Inability to do activities | 96.76 | 91.99 | 0.04 | 95.98 | 92.57 | 0.17 | 92.13 | 95.45 | 0.14 | 94.46 | 91.00 | 0.24 | 98.15 | 77.78 | <0.0001∗ |
| Hip, thigh, or knee weakness | 84.32 | 77.56 | 0.08 | 84.48 | 77.71 | 0.08 | 73.23 | 87.19 | 0.0001∗ | 80.60 | 78.00 | 0.58 | 86.24 | 59.26 | <0.0001∗ |
| Limitations with your mobility or walking | 91.35 | 83.97 | 0.02 | 87.36 | 86.38 | 0.89 | 83.46 | 90.08 | 0.03 | 86.40 | 88.00 | 0.74 | 91.80 | 70.37 | <0.0001∗ |
| Decreased performance in social situations | 93.44 | 81.09 | 0.0001∗ | 72.99 | 92.52 | <0.0001∗ | 80.16 | 91.32 | 0.0005∗ | 83.08 | 95.96 | 0.0006∗ | 83.82 | 90.65 | 0.09 |
| Decreased satisfaction in social situations | 90.22 | 76.92 | 0.0002∗ | 68.97 | 88.82 | <0.0001∗ | 77.87 | 85.95 | 0.02 | 78.79 | 94.00 | 0.0002∗ | 80.11 | 87.04 | 0.12 |
| Difficulty thinking | 29.05 | 26.86 | 0.60 | 21.05 | 31.23 | 0.02 | 25.60 | 29.96 | 0.31 | 27.74 | 27.37 | 1 | 30.29 | 19.23 | 0.03 |
| Emotional issues | 71.04 | 67.2 | 0.42 | 58.96 | 73.83 | 0.0008∗ | 66.80 | 70.83 | 0.38 | 66.08 | 78.79 | 0.02 | 69.15 | 65.42 | 0.48 |
| Impaired body image | 78.26 | 64.42 | 0.0012∗ | 65.52 | 71.74 | 0.15 | 61.26 | 78.51 | <0.0001∗ | 68.18 | 75.00 | 0.22 | 72.68 | 59.26 | 0.009∗ |
| Fatigue | 96.22 | 90.38 | 0.02 | 89.66 | 94.12 | 0.08 | 93.70 | 91.32 | 0.39 | 91.69 | 96.00 | 0.20 | 92.06 | 93.52 | 0.84 |
| Impaired sleep or daytime sleepiness | 83.24 | 74.68 | 0.03 | 70.69 | 81.73 | 0.0064∗ | 77.95 | 77.69 | 1 | 75.82 | 86.00 | 0.03 | 77.25 | 81.48 | 0.43 |
| Pain | 58.24 | 54.34 | 0.45 | 49.71 | 59.06 | 0.06 | 48.21 | 63.90 | 0.0005∗ | 55.70 | 56.12 | 1 | 58.93 | 44.86 | 0.0111∗ |
| Gastrointestinal issues | 67.76 | 43.65 | <0.0001∗ | 42.11 | 58.31 | 0.0006∗ | 49.00 | 56.67 | 0.10 | 48.85 | 68.04 | 0.0009∗ | 52.80 | 51.92 | 0.91 |
| Breathing difficulties | 89.73 | 39.61 | <0.0001∗ | 35.88 | 70.28 | <0.0001∗ | 52.96 | 64.02 | 0.01 | 51.91 | 84.00 | <0.0001∗ | 53.21 | 75.93 | <0.0001∗ |
| Choking or swallowing issues | 78.26 | 55.48 | <0.0001∗ | 22.81 | 85.76 | <0.0001∗ | 60.08 | 68.33 | 0.06 | 55.70 | 96.97 | <0.0001∗ | 55.20 | 93.52 | <0.0001∗ |
| Communication difficulties | 75.14 | 55.70 | <0.0001∗ | 11.18 | 90.37 | <0.0001∗ | 60.32 | 65.69 | 0.23 | 55.10 | 94.00 | <0.0001∗ | 53.62 | 95.37 | <0.0001∗ |
The p-values are from Fisher exact tests comparing responses among the subgroups.
∗Significant p-value ≤0.05 after Benjamini-Hochberg procedure was applied.