Table 3.
Prevalence of symptomatic themes by ALS type.
| Theme | Prevalence, % |
p-value |
|||||
|---|---|---|---|---|---|---|---|
| ALS (n = 434) | PLS (n = 27) | PMA (n = 16) | ALS with frontotemporal dementia (n = 10) | ALS vs. PLS | ALS vs. PMA | ALS vs. ALS with frontotemporal dementia | |
| Problems with your hands or fingers | 89.17 | 85.19 | 75.00 | 60 | 0.52 | 0.10 | 0.02 |
| Problems with your shoulders or arms | 81.57 | 77.78 | 62.50 | 50 | 0.61 | 0.10 | 0.03 |
| Inability to do activities | 93.78 | 100 | 100 | 70 | 0.39 | 0.61 | 0.02 |
| Hip, thigh, or knee weakness | 80.88 | 85.19 | 81.25 | 50 | 0.80 | 1 | 0.03 |
| Limitations with your mobility or walking | 86.87 | 100 | 81.25 | 70 | 0.04 | 0.46 | 0.14 |
| Decreased performance in social situations | 85.65 | 92.59 | 75.00 | 80 | 0.40 | 0.27 | 0.64 |
| Decreased satisfaction in social situations | 81.99 | 88.89 | 75.00 | 70 | 0.45 | 0.51 | 0.40 |
| Difficulty thinking | 25.76 | 38.46 | 40.00 | 60 | 0.17 | 0.24 | 0.03 |
| Emotional issues | 67.67 | 80.77 | 66.67 | 80 | 0.20 | 1 | 0.51 |
| Impaired body image | 69.05 | 70.37 | 93.75 | 70 | 1 | 0.05 | 1 |
| Fatigue | 93.09 | 92.59 | 81.25 | 90 | 0.71 | 0.10 | 0.52 |
| Impaired sleep or daytime sleepiness | 78.11 | 77.78 | 81.25 | 60 | 1 | 1 | 0.24 |
| Pain | 54.88 | 70.37 | 43.75 | 60 | 0.16 | 0.45 | 1 |
| Gastrointestinal issues | 52.46 | 55.56 | 37.50 | 70 | 0.84 | 0.31 | 0.35 |
| Breathing difficulties | 59.77 | 48.15 | 43.75 | 40 | 0.31 | 0.21 | 0.33 |
| Choking or swallowing issues | 64.27 | 70.37 | 43.75 | 60 | 0.68 | 0.11 | 0.75 |
| Communication difficulties | 62.70 | 77.78 | 50.00 | 60 | 0.15 | 0.31 | 1 |
The p-values are from Fisher exact tests comparing responses among the subgroups.