Table 3.

Efficacy and safety of therapeutic applications

	Efficacy			Safety
	Efficacy endpoint	Treatment duration	Long-term efficacy after treatment	Safety endpoint
reSET	Abstinence at 9–12 weeks and retention in outpatient therapy	12 Weeks	–	Not prescribed
reSET-O	Longest continuous abstinence, total abstinence, and days in retained in the treatment at 12 weeks	12 Weeks	–	Not prescribe
Somryst	Patient health questionnaire at 6 months	9 Weeks	18 Month	Not prescribe
EndeavorRx	Change in the test of variables of attention–attention performance index at 4 weeks	4 Weeks	1 Month	Not prescribed
NightWare	Pittsburgh Sleep Quality Index Scale at 30 days	30 Days	–	Epworth Sleepiness Scale and Columbia Suicide Severity Rating Scale
Parallel	IBS Symptom Severity Score and Work and Social Adjustment Scale at 12 months	12 Weeks	9 Month	Not prescribed
The CureApp smoking cessation system	Continuous abstinence rate from weeks 9–24	24 Weeks	6 Month	Not prescribed