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. 2022 Sep 7;33(1):162–171. doi: 10.1007/s00330-022-09033-6

Table 1.

Comparison of the clinical characteristics of patients and DECT characteristics of lymph nodes between metastasis and non-metastasis

Patients
Clinical characteristics Metastasis (n = 33) Non-metastasis (n = 70) p values
Age median, range (years) 55.5 (37–70) 52.3 (31–79) 0.102
HPV positive 0 (0%) 1 (1.4%) 0.168
Sex 0.336
  Male 30 (90.9%) 67 (95.7%)
  Female 3 (9.1%) 3 (4.3%)
T category < 0.001**
  T1 0 (0%) 19 (21.1%)
  T2 17 (51.5%) 40 (57.1%)
  T3 14 (42.4%) 11 (15.8%)
  T4 2 (6.1%) 0 (0%)
Location of OSCC 0.536
  Tongue 16 (48.5%) 34 (48.6%)
  Buccal mucosa 10 (30.3%) 23 (32.9%)
  Floor of mouth 7 (21.2%) 2 (2.9%)
  Gingiva 0 (%) 11 (15.6%)
Lymph nodes
DECT characteristics Metastasis (n = 158) Non-metastasis (n = 241) p values
T category < 0.001**
  T1 0 (0%) 35 (14.5%)
  T2 52 (32.9%) 111 (46.1%)
  T3 93 (58.9%) 89 (36.9%)
  T4 13 (8.2%) 6 (2.5%)
Location of OSCC 0.752
  Tongue 72 (45.6%) 108 (44.8%)
  Buccal mucosa 24 (15.1%) 82 (34.0%)
  Floor of mouth 62 (39.3%) 17 (7.1%)
  Gum 0 (0%) 34 (14.1%)
Length (mm) 14.5 ± 6.4 10.0 ± 3.0 < 0.001**
Width (mm) 11.1 ± 5.1 6.8 ± 2.1 < 0.001**
Aspect ratio 1.34 ± 0.24 1.52 ± 0.43 < 0.001**
Necrosis < 0.001**
  Yes 67 (42.4%) 13 (5.4%)
  No 91 (57.6%) 228 (94.6%)
Capsule infiltration < 0.001**
  Yes 48 (30.4%) 3 (1.2%)
  No 110 (69.6%) 238 (98.8%)
Extranodal extension < 0.001**
  Yes 24 (15.2%) 1 (0.4%)
  No 134 (84.8%) 240 (99.6%)
Aggregation < 0.001**
  Yes 33 (20.9%) 0 (0%)
  No 125 (79.1%) 241 (100%)

OSSC oral squamous cell carcinoma, DECT dual-energy computed tomography, HPV human papillomavirus. **p < 0.01