Table 2.
Univariable and multivariable predictors of arrhythmia free survival with a Cox regression.
| Univariable analysis | Multivariable analysis 1 | Multivariable analysis 2 | ||||
|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age (years) | 1.011 (0.977–1.047) | 0.526 | ||||
| BMI (kg/m2) | 1.032 (0.982–1.085) | 0.213 | ||||
| BSA (m2) | 1.666 (0.561–4.951) | 0.358 | ||||
| Sex, male | 0.576 (0.274–1.211) | 0.146 | ||||
| Hypertension | 1.005 (0.496–2.035) | 0.989 | ||||
| Coronary artery disease | 0.831 (0.357–1.935) | 0.668 | ||||
| Congestive heart failure | 1.571 (0.762–3.238) | 0.221 | ||||
| Obstructive sleep apnea | 1.056 (0.455–2.453) | 0.899 | ||||
| Stroke | 0.273 (0.037–2.007) | 0.202 | ||||
| Hyperlipidemia | 1.235 (0.608–2.507) | 0.559 | ||||
| Diabetes mellitus | 1.497 (0.669–3.35) | 0.326 | ||||
| Non-paroxysmal AF | 1.917 (0.945–3.888) | 0.071 | 0.781 (0.333 to 1.83) | 0.569 | 1.174 (0.559, 2.464) | 0.671 |
| RF ablation | 1.794 (0.733–4.39) | 0.201 | ||||
| LA EAT index (mL/m2) | 1.089 (1.055–1.124) | < 0.001 | 1.089 (1.049 to 1.131) | < 0.001 | ||
| LA EAT index >14.29 mL/m2 | 7.331 (2.227–24.135) | 0.001 | 6.397 (1.87, 21.88) | 0.003 | ||
| Total EAT index (mL/m2) | 1.009 (0.996–1.022) | 0.17 | ||||
| LA volume index (mL/m2) | 1.019 (1.005–1.034) | 0.009 | 1.008 (0.991 to 1.025) | 0.343 | 1.009 (0.993, 1.025) | 0.281 |
| LA fibrosis (%) | 1.038 (0.991–1.087) | 0.119 | ||||
| AF duration prior to ablation (months) | 1.007 (0.996, 1.017) | 0.203 | ||||
BMI, body mass index; BSA, body surface area; AF, atrial fibrillation; RF, radiofrequency; LA, left atrial; EAT, epicardial adipose tissue.