Table 2.

Multiple linear regression associations of blood metal levels with serum uric acid in adults.

Metals	Continuous log2-transformed Metals	Quartile 1	Quartile 2	Quartile 3	Quartile 4	P for trend
		β	β (95%CI)	β (95%CI)	β (95%CI)
Mercury, µg/L	0.046 (0.032, 0.059) ***	0.00 [Reference]	0.084 (0.032, 0.136) **	0.100 (0.046, 0.153) ***	0.188 (0.133, 0.244) ***	<0.001
Manganese, µg/L	0.009 (-0.031, 0.048)	0.00 [Reference]	-0.016 (-0.069, 0.036)	0.002 (-0.051, 0.056)	0.020 (-0.036, 0.076)	0.394
Lead, µg/dL	0.107 (0.085, 0.129) ***	0.00 [Reference]	0.111 (0.058, 0.166) ***	0.193 (0.135, 0.250) ***	0.287 (0.225, 0.350) ***	<0.001
Cadmium, µg/L	-0.002 (-0.023, 0.019)	0.00 [Reference]	-0.029 (-0.082, 0.024)	-0.053 (-0.110, 0.005)	0.015 (-0.053, 0.083)	0.889
Selenium, µg/L	0.119 (0.020, 0.218) *	0.00 [Reference]	0.082 (0.030, 0.135) **	0.057 (0.005, 0.110) **	0.114 (0.061, 0.168) ***	<0.001

Model was adjusted as age, sex, education level, race, poverty, smoker, alcohol user, energy intake levels, sedentary time, BMI, total cholesterol, high-density lipoprotein cholesterol, eGFR, urinary creatinine, urinary albumin, diuretics, anti-gout medications, beta-blockers, diabetes, and hypertension.

CI, confidence interval; ^* p < 0.05, ^** p < 0.01 and ^*** p < 0.001.