Table 2.
Ventilatory mechanics and gas analysis.
| Characteristics | Control | Titration | p | ||
|---|---|---|---|---|---|
| (n = 24) | (n = 24) | Time | Group | Inter | |
| Compliance (mL cmH2O−1) | < 0.001 | 0.02 | < 0.001 | ||
| immediately after intubation | 62.5(10.4) | 60.8(9.3) | |||
| 10 min after PNP | 32.3(6.6) | 29.3(5.4) | |||
| 1 h after PNP | 29.4(6.1) | 36.7(8.3)** | |||
| 10 min after deflation of PNP | 43.0(11.8) | 52.5(11.1)* | |||
| end of surgery | 44.1(10.7) | 55.1(10.3)** | |||
| Ppeak (cmH2O) | < 0.001 | 0.08 | < 0.001 | ||
| immediately after intubation | 14(3.9) | 14.5(2.6) | |||
| 10 min after PNP | 21.5(3.8) | 22.1(2.6) | |||
| 1 h after PNP | 23(4.6) | 26.3(2.5)* | |||
| 10 min after deflation of PNP | 17.7(3.1) | 20.5(3.5)* | |||
| end of surgery | 17.8(3.2) | 17.1(3.8) | |||
| Pplat (cmH2O) | < 0.001 | 0.06 | 0.01 | ||
| immediately after intubation | 11.5(4.1) | 12.2(2.8) | |||
| 10 min after PNP | 19.5(4.0) | 20.0(3.0) | |||
| 1 h after PNP | 21.5(4.0) | 24.5(2.1)* | |||
| 10 min after deflation of PNP | 15.2(3.2) | 17.9(3.7)* | |||
| end of surgery | 14.9(2.8) | 14.9(3.7) | |||
| PaCO2 | < 0.001 | 0.89 | 0.39 | ||
| immediately after intubation | 35.9(4.1) | 34.0(4.1) | |||
| 1 h after PNP | 41.9(4.0) | 41.9(5.5) | |||
| immediately after extubation | 45.0(7.2) | 46.3(6.0) | |||
| 1 h after extubation | 39.4(4.3) | 40.1(4.5) | |||
| pH | < 0.001 | 0.05 | 0.33 | ||
| immediately after intubation | 7.41(0.028) | 7.43(0.039) | |||
| 1 h after PNP | 7.34(0.042) | 7.36(0.047) | |||
| immediately after extubation | 7.32(0.045) | 7.32(0.046) | |||
| 1 h after extubation | 7.35(0.039) | 7.36(0.045) | |||
Values are the mean (SD) or number (%). Values are the mean (SD). Ppeak airway peak pressure; Pplat airway plateau pressure; PNP pneumoperitoneum. *p < 0.05; **p < 0.01 compared to the control group.