TABLE 3.
CircRNA name | Cofactor | Interaction mode | Target | Tissue/disease | Function | References |
---|---|---|---|---|---|---|
ACR | DNMT3B | Recruit | Pink1 | Myocardial ischemia/infarction | Autophagy | Zhou et al. (2019b) |
Circ_6790 | CBX7—DNMTs | Recruit | S100A11 | Pancreatic ductal adenocarcinoma | Cell proliferation, apoptosis, metastasis, immune escape | Gao et al. (2022) |
Hsa_circ_001291 | DNMT1 | Expression | CD11a; CD70 | Systemic lupus erythematosus | Zhang et al. (2018) | |
Circ-Amotl1 | STAT3—DNMT3A | Expression | miR-17-5p | Wound healing | Cell adhesion, migration, proliferation, wound repair | Yang et al. (2017) |
FECR1 | TET1; DNMT1 | Recruit; expression | FLI1; SERTED2 | Breast cancer | Tumor invasion, metastasis | Chen et al. (2018) |
Circ_0040809 | miR-515-5p—DNMT1 | ceRNA | Colorectal cancer | Cell proliferation, migration, apoptosis | Mao et al. (2021) | |
CircSOD2 | miR-502-5p—DNMT3A | ceRNA | SOCS3 | Hepatocellular carcinoma | JAK2/STAT3 signaling | Zhao et al. (2020b) |
CircMEMO1 | miR-106b-5p—TET1 | ceRNA | TCF21 | Hepatocellular carcinoma | Cell proliferation, invasion, metastasis, EMT, sorafenib sensitivity | Dong et al. (2021) |
CircTRIM33–12 | miR-191—TET1 | ceRNA | WWC3; TP53INP1; ULBP1; JHDM1D | Hepatocellular carcinoma | Cell proliferation, migration, invasion, immune evasion | Zhang et al. (2019a) |
CircIBTK | miR-29b | — | Genome wide | Systemic lupus erythematosus | AKT signaling | Zhang et al. (2019a) |
Circ-ATAD1 | — | — | miR-34b | Acute myeloid leukemia | Cell proliferation | Wu et al. (2021b) |
Circ-ATAD1 | — | — | miR-10a | Endometrial cancer | Cell invasion, migration | Yang et al. (2021a) |
CircFAT1 | — | — | miR-21 | Endometrial cancer | Cell stemness increase | Wu et al. (2021a) |
CircSEPT9 | — | — | miR-186 | Endometrial cancer | Cell invasion, migration | Guo et al. (2022) |
CircRIMS | — | — | miR-613 | Esophageal squamous cell carcinoma | Cell proliferation | Wan et al. (2021) |
CircSKA3 | — | — | miR-1 | Glioblastoma | Cell proliferation | Zhou et al. (2021a) |
CircFADS2 | — | — | miR-195-5p | Osteoarthritis | Apoptosis | Zhang et al. (2021b) |