Figure A1.

Dezocine inhibits ovarian cancer cell proliferation and colony formation. (a and b) ES-2 (a) and SKOV3 (b) cells were treated with various concentration levels of dezocine (0, 2.5, 5, 10, 20, 30, 40, 50, 60, 80, 120, and 200 μg/mL) for 24 h, and cell viability was measured by CCK8 assay. (c and d) Cell viability was measured by CCK8 assay in ES-2 (c) and SKOV3 (d) cells treated with dezocine for 0, 24, 48, and 72 h, respectively. (e and f) Colony formation assay showing inhibitory effects of dezocine on ES-2 (e) and SKOV3 (f) cells. (g) Quantitative analysis of colony formation results. ^* P < 0.05, ^** P < 0.01.