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. 2022 Dec 2;12:1016958. doi: 10.3389/fonc.2022.1016958

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Copyright © 2022 Seborova, Hlavac, Holy, Bjørklund, Fleischer, Rob, Hruda, Bouda, Mrhalova, Allah, Vodicka, Fiala, Soucek, Kristensen, Vodickova and Vaclavikova

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially expressed DNA repair genes based on the response of EOC patients to platinum based chemotherapy. Analysis of differential expression between platinum-sensitive patients and the platinum-resistant ones showed four differentially expressed genes – (A) DDB2, (B) PRPF19, (C) HELQ and (D) MAD2L2. EOC patients were divided as platinum-sensitive (N=37, purple color) and platinum-resistant (N=23, orange color) based on the platinum resistance status determined by platinum-free interval (PFI).