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. 2022 Dec 2;12:1016958. doi: 10.3389/fonc.2022.1016958

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Copyright © 2022 Seborova, Hlavac, Holy, Bjørklund, Fleischer, Rob, Hruda, Bouda, Mrhalova, Allah, Vodicka, Fiala, Soucek, Kristensen, Vodickova and Vaclavikova

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FAAP20 gene expression compared to (A) PRKDC and (B) XPC mutations. Differential expression of FAAP20 between patient groups – platinum-sensitive (N = 32, pink color), platinum-resistant harboring mutant PRKDC/XPC genes (N = 2, purple color) and platinum-resistant harboring wild type PRKDC/XPC genes (N = 18, green color). All P-values are declared after adjusting for FDR. Patients were divided based on the platinum resistance status determined by platinum-free interval (PFI). SNV (single nucleotide polymorphism/variant), DEL (deletion), DNP (double nucleotide polymorphism/variant), INS (insertion).