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. 2022 Dec 2;12:1016958. doi: 10.3389/fonc.2022.1016958

Table 3.

Associations of whole DNA repair gene methylation profile with clinical data of EOC patients (N=73, only significant result with P ≤ 0.01 are listed).

Gene Age pM Grade a EOC type b
APLF P=0.009 NS NS NS
FAN1 P=0.007 NS NS NS
PARP3 P=0.01 NS NS NS
POLL P=0.0002 NS NS NS
APEX2 NS NS NS P=0.004
ERCC2 NS NS NS P=0.004
FANCB NS NS NS P=0.001
RAD51C NS NS P=0.003 P=0.001
HUS1 NS NS NS P=0.008
MPG NS NS NS P=0.007
MSH5 NS NS NS P=0.001
POLM NS P=0.002 NS NS
OBFC2B NS NS P=0.003 NS
TREX1 NS NS P=0.007 NS
a

Patients divided into two groups: Group 1 (Grade 1 + Grade 2), Group 2 (Grade 3).

b

Patients divided into two groups: Group 1 (HGSC type), Group 2 (Other types).

Significant result after FDR correction in bold. NS, not significant.