TABLE 3.
The coverage rate of the population estimates for the volume of distribution for the missing data handling methods under different scenarios with 20% missing values in BW
| LD | Mean | Norm | PMM | RF | ANN | |
|---|---|---|---|---|---|---|
| Linear | ||||||
| MCAR | 100% | 100% | 100% | 100% | 100% | 100% |
| MAR | 82% | 24% | 100% | 100% | 100% | 100% |
| Nonlinear | ||||||
| MCAR | 98% | 76% | 100% | 100% | 98% | 100% |
| MAR | 98% | 2% | 84% | 98% | 92% | 90% |
| Outside observed range | 100% | 0% | 88% | 4% | 2% | 74% |
Abbreviations: ANN, artificial neural network; BW, birth weight; LD, listwise deletion; MAR, missing at random; MCAR, missing completely at random; PMM, predictive mean matching; RF, random forest; V pop, population volume of distribution.