Table 2.
Data analysis by the several reviewers.
| Diagnostic metrics | P | S1 | S2 | S3 | S4 | S5 | All |
|---|---|---|---|---|---|---|---|
| Value (95% CI) | Value (95% CI) | Value (95% CI) | Value (95% CI) | Value (95% CI) | Value (95% CI) | Value (95% CI) | |
| Accuracy | 85.8% (80.1–90.3) | 88.8% (83.6–92.9) | 84.8% (79.0–89.5) | 86.3% (80.7–90.8) | 77.7% (71.2–83.3) | 76.1% (69.6–81.9) | 83.2% (81.0–85.3) |
| Sensitivity | 83.0% (74.5–89.6) | 86.8% (78.8–92.6) | 89.0% (80.7–94.6) | 91.5% (84.5–96.0) | 75.5% (66.2–83.3) | 69.8% (60.1–78.) | 81.3% (78.0–84.2) |
| Specificity | 89.0% (80.7–94.6) | 91.2% (83.4–96.1) | 81.1% (72.4–88.1) | 80.2% (70.5–87.8) | 80.2% (70.5–87.8) | 83.5% (74.3–90.5) | 85.5% (82.3–88.4) |
| PPV | 89.8% (83.0–94.0) | 92.0% (85.5–95.7) | 80.2% (73.0–85.8) | 84.3% (78.0– 89.1) | 81.6% (74.3–87.2) | 83.1% (75.3–88.8) | 86.7% (84.2–88.9) |
| NPV | 81.8% (74.6–87.3) | 85.6% (78.4–90.6) | 89.6% (82.6–94.0) | 89.0% (81.1– 93.9) | 73.7% (66.4–79.9) | 70.4% (63.7–76.3) | 79.7% (76.9–82.2) |
| ROC (AUC) | 0.90 (0.86–0.94) | 0.91 (0.87–0.95) | 0.88 (0.84–0.93) | 0.85 (0.81–0.90) | 0.81 (0.76–0.86) | 0.83 (0.78–0.88) | 0.86 (0.84–0.88) |
P, pathologist; S, surgeon; PPV, positive predictive value; NPV, negative predictive value; 95% CI, 95% confidence interval; ROC, receiver operating characteristic; AUC, area under the curve.