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. 2022 Dec 14;12(12):e062188. doi: 10.1136/bmjopen-2022-062188

Table 2.

OR for associations between serum concentrations of inflammatory factors (cytokines (n=4), chemokines (n=6), proinflammatory cytokines (n=5), vascular injury (n=1)) in type 2 diabetes with short-term disease duration (<10 years, n=44) and long-term disease duration (>10 years, n=50) unadjusted and adjusted for age and BMI

Unadjusted model Adjusted model
Or (95% CI) P value Or (95% CI) P value
Cytokines IL-7 1.03 (0.93 to 1.15) 0.565 1.04 (0.93 to 1.18) 0.466
IL-12
/IL-23p40
1.00 (1.00 to 1.00) 0.446 1.00 (0.99 to 1.01) 0.717
IL-15 1.51 (0.74 to 3.10) 0.256 1.32 (0.62 to 2.79) 0.471
IL-16 1.00 (1.00 to 1.00) 0.832 1.00 (1.00 to 1.00) 0.813
Chemokines Eotaxin 1.00 (1.00 to 1.00) 0.887 1.00 (1.00 to 1.00) 0.687
IP-10 1.00 (1.00 to 1.00) 0.512 1.00 (1.00 to 1.00) 0.244
MCP-1 1.00 (1.00 to 1.00) 0.864 1.00 (1.00 to 1.00) 0.523
MDC 1.00 (1.00 to 1.00) 0.810 1.00 (1.00 to 1.00) 0.319
MIP-1β 1.00 (0.99 to 1.01 0.992 1.00 (0.99 to 1.01) 0.916
TARC 1.00 (1.00 to 1.00) 0.719 1.00 (1.00 to 1.00) 0.260
Proinflammatory cytokines IL-6 1.34 (0.79 to 2.27) 0.271 1.21 (0.70 to 2.09) 0.504
IL-8 1.00 (0.94 to 1.06) 0.983 1.00 (0.94 to 1.06) 0.904
IL-10 111.85 (2.86 to 4377.78) 0.012 103.97 (2.30 to 4699.58) 0.017
IFN-γ 1.02 (0.97 to 1.08) 0.438 1.02 (0.96 to 1.09) 0.447
TNF-α 1.69 (0.70 to 4.12) 0.246 1.78 (0.69 to 4.62) 0.234
Vascular injury CRP 1.00 (1.00 to 1.00) 0.697 1.00 (1.00 to 1.00) 0.713

Boldface font indicates statistical significance (p<0.05).

BMI, body mass index; CRP, C reactive protein; IL, interleukin; TNF, tumour necrosis factor.