Table 2.
OR for associations between serum concentrations of inflammatory factors (cytokines (n=4), chemokines (n=6), proinflammatory cytokines (n=5), vascular injury (n=1)) in type 2 diabetes with short-term disease duration (<10 years, n=44) and long-term disease duration (>10 years, n=50) unadjusted and adjusted for age and BMI
Unadjusted model | Adjusted model | ||||
Or (95% CI) | P value | Or (95% CI) | P value | ||
Cytokines | IL-7 | 1.03 (0.93 to 1.15) | 0.565 | 1.04 (0.93 to 1.18) | 0.466 |
IL-12 /IL-23p40 |
1.00 (1.00 to 1.00) | 0.446 | 1.00 (0.99 to 1.01) | 0.717 | |
IL-15 | 1.51 (0.74 to 3.10) | 0.256 | 1.32 (0.62 to 2.79) | 0.471 | |
IL-16 | 1.00 (1.00 to 1.00) | 0.832 | 1.00 (1.00 to 1.00) | 0.813 | |
Chemokines | Eotaxin | 1.00 (1.00 to 1.00) | 0.887 | 1.00 (1.00 to 1.00) | 0.687 |
IP-10 | 1.00 (1.00 to 1.00) | 0.512 | 1.00 (1.00 to 1.00) | 0.244 | |
MCP-1 | 1.00 (1.00 to 1.00) | 0.864 | 1.00 (1.00 to 1.00) | 0.523 | |
MDC | 1.00 (1.00 to 1.00) | 0.810 | 1.00 (1.00 to 1.00) | 0.319 | |
MIP-1β | 1.00 (0.99 to 1.01 | 0.992 | 1.00 (0.99 to 1.01) | 0.916 | |
TARC | 1.00 (1.00 to 1.00) | 0.719 | 1.00 (1.00 to 1.00) | 0.260 | |
Proinflammatory cytokines | IL-6 | 1.34 (0.79 to 2.27) | 0.271 | 1.21 (0.70 to 2.09) | 0.504 |
IL-8 | 1.00 (0.94 to 1.06) | 0.983 | 1.00 (0.94 to 1.06) | 0.904 | |
IL-10 | 111.85 (2.86 to 4377.78) | 0.012 | 103.97 (2.30 to 4699.58) | 0.017 | |
IFN-γ | 1.02 (0.97 to 1.08) | 0.438 | 1.02 (0.96 to 1.09) | 0.447 | |
TNF-α | 1.69 (0.70 to 4.12) | 0.246 | 1.78 (0.69 to 4.62) | 0.234 | |
Vascular injury | CRP | 1.00 (1.00 to 1.00) | 0.697 | 1.00 (1.00 to 1.00) | 0.713 |
Boldface font indicates statistical significance (p<0.05).
BMI, body mass index; CRP, C reactive protein; IL, interleukin; TNF, tumour necrosis factor.