Endoscopic appearance of caecum (A, C, E) and descending colon (B, D, F). (A) Caecum at first colonoscopy, (B) descending colon at first colonoscopy, (C) caecum when presented with acute severe colitis, (D) descending colon when presented with acute severe colitis, (E) caecum at colonoscopy 7 days later after ciclosporin therapy, (F) descending colon 7 days later after ciclosporin therapy.