Table 5. Univariate and multivariate analyses of minor amputations among inpatients treated for PAOD (2016–2018).

Minor amputation	Univariate analysis		Multivariate analysis (Nagelkerke’s pseudo-R²: 0.414)
	Odds ratio	p-value	Odds ratio	p-value
PAOD stage − Fontaine IIb (ref) − Fontaine III − Fontaine IVu − Fontaine IVg	1.00 7.79 [6.19; 9.81] 200.24 [165.61; 242.11] 1153.42 [954.75; 393.43]	< 0.001 < 0.001 < 0.001	1.00 8.07 [6.41; 10.16] 206.44 [170.70; 249.67] 1149.46 [951.22; 1389.00]	< 0.001 < 0.001 < 0.001
Age (continuous)	1.03 [1.03; 1.03]	< 0.001	1.00 [1.00; 1.00]	< 0.001
Sex − male (ref) − female	1.00 0.65 [0.63; 0.66]	< 0.001	1.00 0.60 [0.59; 0.62]	< 0.001
Hypertension	0.86 [0.85; 0.88]	< 0.001	1.05 [1.03; 1.08]	< 0.001
Type 2 diabetes mellitus	2.11 [2.07; 2.15]	< 0.001	1.34 [1.31; 1.37]	< 0.001
Dyslipidemia	0.68 [0.67; 0.69]	< 0.001	0.99 [0.96; 1.01]	0.268
Care level − Maximum care (≥ 800) (ref) − Central care (500–799) − Standard care (300–499) − Basic care (100–299) − Minimum care (< 100)	1.00 1.01 [0.98; 1.04] 1.00 [0.97; 1.02] 0.93 [0.90; 0.96] 0.62 [0.56; 0.69]	0.605 0.770 < 0.001 < 0.001	1.00 1.07 [1.04; 1.11] 1.08 [1.05; 1.11] 0.99 [0.96; 1.02] 0.69 [0.61; 0.77]	< 0.001 < 0.001 0.560 < 0.001
Certification status − Not certified (ref) − Certified	1.00 0.96 [0.94; 0.98]	< 0.001	1.00 1.04 [1.01; 1.06]	0.004

The odds ratios are given with their 95% confidence intervals. In the multivariate analysis they were adjusted for all variables (PAOD stage, age, sex, hypertension, type 2 diabetes mellitus, dyslipidemia, care level, and certification status).

IVg, Stage IV with gangrene; IVu, stage IV with ulceration; ref, reference; PAOD, peripheral arterial occlusive disease