Figure 2. NA-specific humoral and cellular immune responses in vaccinated mice.
A. NA-specific antibody endpoint titers determined by ELISA. B. NAI test results against different influenza virus strains. The OD450 values were compared with the virus only. C. Antibody subtype IgG2a/IgG1 ratio analysis. D. NA-specific antibody-secreting cells in the bone marrow. E-F, NA-specific IFN-γ or IL-4 secreting splenocytes. (n = 5; * p<0.05; **p < 0.01; ***p < 0.001; ns, p > 0.05)