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. 2022 Dec 16;10:230. doi: 10.1186/s40168-022-01425-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Microbial features associated with viral infection. Linear mixed models were used to identify OTU associated with A detection of any virus and B samples with any enterovirus. Linear mixed models were used to identify C proteins associated with the detection of any enterovirus and D proteins associated with any mastadenovirus. The 28 proteins associated with mastadenovirus infection are shown in a heatmap grouped using non-hierarchal clustering. Taxonomic and functional characteristics of the variables associated with each protein are indicated by the color in the legend