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. 2022 Dec 14;63(13):14. doi: 10.1167/iovs.63.13.14

Table 1.

Drugs Included in the Screen

Drug Target/Mechanism of Action Clinical Trials Phase References
Trabectedin RNA Pol II, DNA-bound proteins, tumor microenvironment/multitarget DNA-damaging agent III Monk et al.36
CX-4945 Casein kinase 2, Cdc2-like kinases Ib/II Borad et al.37
Foretinib C-MET, VEGFR2, TAM (TYRO, Axl, MERTK) receptors II Rayson et al.38
RG7112 MDM2–p53 interaction/p53 activator I Andreeff et al.39