Table 2.
The results of laboratory tests on admission according to the acute pancreatitis severity
| Variable | MAP(n = 42) | MSAP(n = 35) | SAP(n = 17) | P-value |
|---|---|---|---|---|
| White blood cell count, × 109/L | 9.830 ± 4.188 | 12.028 ± 4.320& | 16.350 ± 4.527$# | < 0.001 |
| Red blood cell count, × 1012/L | 4.647 ± 0.593 | 4.802 ± 0.667 | 5.374 ± 0.828$# | 0.001 |
| Hematocrit, % | 43.752 ± 13.922 | 45.197 ± 17.827 | 48.635 ± 6.860 | 0.513 |
| Platelet count, × 1012/L | 191.881 ± 62.304 | 225.086 ± 84.156 | 243.235 ± 82.945# | 0.034 |
| CRP, mg/L | 54.088 ± 67.037 | 92.224 ± 75.537 | 194.541 ± 152.605$# | < 0.001 |
| ALT, U/L | 54.333 ± 152.244 | 93.870 ± 168.934 | 252.682 ± 602.560# | 0.063 |
| AST, U/L | 73.595 ± 133.175 | 86.691 ± 197.879 | 228.735 ± 600.135 | 0.168 |
| Total bilirubin, μmol/L | 22.000 (14.500, 33.850) | 23.400 (18.100, 39.900) | 38.000 (15.65, 126.6) | 0.196 |
| Direct bilirubin, μmol/L | 7.800 (3.075, 12.200) | 10.900 (5.900,1 6.200) | 28.000 (10.000,103.500)$# | 0.001 |
| Triglyceride, mmol/L | 4.238 ± 5.253 | 10.244 ± 28.837 | 8.136 ± 7.407 | 0.350 |
| Creatinine, μmol/L | 41.064 ± 29.968 | 51.709 ± 30.791 | 82.206 ± 43.672$# | < 0.001 |
| Urea, mmol/L | 7.514 ± 16.428 | 4.809 ± 2.258 | 5.724 ± 2.599 | 0.563 |
| Procalcitonin, ng/ml | 0.188 ± 0.285 | 1.026 ± 2.305 | 5.040 ± 11.073$# | 0.003 |
| Amylase, U/L | 727.219 ± 981.935 | 924.914 ± 853.368 | 895.653 ± 790.804 | 0.602 |
| sTIM-3, pg/ml | 911.615 ± 565.535 | 1462.801 ± 688.925& | 2152.698 ± 632.143$# | < 0.001 |
| IL-6, pg/ml | 42.902 ± 28.821 | 119.501 ± 74.666& | 323.593 ± 62.933$# | < 0.001 |
| IL-10, pg/ml | 1206.080 ± 566.251 | 964.443 ± 603.482 | 760.253 ± 200.418# | 0.012 |
| APACHE II score, points | 3.619 ± 2.230 | 5.743 ± 3.119& | 12.647 ± 8.177$# | < 0.001 |
| BISAP score, points | 1.214 ± 0.606 | 2.400 ± 0.847& | 3.529 ± 0.717$# | < 0.001 |
| MCTSI score, points | 1.190 ± 0.994 | 4.057 ± 1.413& | 4.235 ± 1.562# | < 0.001 |
Abbreviations: MAP Mild acute pancreatitis, MSAP Moderately severe acute pancreatitis, SAP Severe acute pancreatitis, CRP C-reactive protein, ALT Alanine aminotransferases, AST Aspartate aminotransferases, IL-6 Interleukin-6, IL-10 Interleukin-10, APACHE II Acute physiology and chronic health evaluation II, BISAP Bedside index for severity in acute pancreatitis, MCTSI Modified computed tomography severity index
P < 0.05 was considered statistically significant. &P < 0.05, MAP versus MSAP; #P < 0.05, MAP versus SAP; $P < 0.05, MSAP versus SAP