Table 4.
Diagnostic value for different scoring systems versus sTIM-3 in SAP
| Variable | AUC (95% CI) | Cut-off | Specificity (%) | Sensitivity (%) | Accuracy (%) | +LR | -LR | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|---|---|---|
| sTIM-3 | 0.853 (0.768-0.938) | 1400.247 | 68.83 | 94.12 | 73.4 | 3.02 | 0.086 | 40 | 98.15 |
| BISAP | 0.914 (0.865-0.963) | 3 | 76.62 | 100 | 80.85 | 4.278 | 0 | 48.57 | 100 |
| APACHE-II | 0.855 (0.742-0.968) | 12 | 100 | 58.82 | 92.55 | Inf | 0.412 | 100 | 91,67 |
| MCTSI | 0.746 (0.633-0.860) | 4 | 59.74 | 76.47 | 62.77 | 1.9 | 0.394 | 29.55 | 92 |
Abbreviations: sTIM-3 Soluble T cell immunoglobulin and mucin domain-3, APACHE II Acute physiology and chronic health evaluation II, BISAP Bedside index for severity in acute pancreatitis, MCTSI Modified computed tomography severity index, AUC Area under the curve, CI Confidence interval, LR Likelihood ratio, PPV Positive predictive value, NPV Negative predictive value