Table 1.
Comparison of Traditional Pneumococcal Serotyping with Serotyping Performed Using Metatranscriptomics
| Sample | Culture Pnc | Metatranscriptomics Pnc | Culture Serotype | Meta Serotype |
|---|---|---|---|---|
| CTL-BHN1 | + | (+) | 11A | ND* |
| CTL-BHN2 | + | + | 19A | 19A |
| CTL-BHN3 | — | (+) | — | ND* |
| CTL-BHN4 | — | + | — | ND* |
| CTL-BHN5 | + | + | 15B | 15B/15C |
| CTL-BHN6 | + | + | 21 | 21 |
| CTL-BHN7 | — | (+) | — | ND* |
| CTL-BHN8 | — | — | — | — |
| CTL-BHN9 | + | + | 35F | ND* |
| CTL-BHN10 | — | (+) | — | ND* |
| CTL-BHN11 | — | — | — | — |
| CTL-BHN12 | — | — | — | — |
| CTL-BHN13 | — | — | — | — |
| CTL-BHN14 | + | + | 35F | ND* |
| CTL-BHN15 | — | — | — | — |
| CTL-BHN16 | — | + | — | ND* |
| CTL-BHN17 | — | — | — | — |
| CTL-BHN18 | — | (+) | — | ND* |
| CTL-BHN19 | — | — | — | — |
| CTL-BHN20 | — | + | — | ND* |
| CASES-BHN21 | + | + | 35F | 35F |
| CASES-BHN22 | + | + | 21 | 21 |
| CASES-BHN23 | — | (+) | — | ND* |
| CASES-BHN24 | + | + | 35B | ND* |
| CASES-BHN25 | — | + | — | ND† |
| CASES-BHN26 | + | + | 15A | 15A/15F |
| CASES-BHN27 | + | + | 3 | 3 |
| CASES-BHN28 | — | (+) | — | ND* |
| CASES-BHN29 | + | + | 22F | 22F |
| CASES-BHN30 | — | — | — | — |
| CASES-BHN31 | — | — | — | — |
| CASES-BHN32 | + | + | 35F | ND* |
| CASES-BHN33 | — | — | — | — |
| CASES-BHN34 | + | (+) | 15B | ND* |
| CASES-BHN35 | + | + | 23B | ND* |
| CASES-BHN36 | — | (+) | — | ND* |
| CASES-BHN37 | + | + | 35F | 35F |
| CASES-BHN38 | — | — | — | — |
| CASES-BHN39 | — | — | — | — |
| CASES-BHN40 | + | + | 15B | 15B/15C |
Definition of abbreviation: Pnc = pneumococci.
(+) indicates low abundance reads.
*
Capsular region not determined.
†
Only cpsA was captured, and the serotype could not be determined.