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. 2022 Nov 18;14(11):e31660. doi: 10.7759/cureus.31660

Table 2. Assessment of appropriateness of carbapenem therapy.

Characteristic Number of patients (%) (n = 20)
Appropriate 13 (65%)
Targeted therapy supported by cultures 10
Septic shock or severe infection with a history of infection in the past 6 months with a B-lactam-resistant organism 0
Septic shock or severe infection with a history of multiple antibiotics given or colonization with a B-lactam-resistant organism 0
Severe neutropenia with a history of multiple antibiotics given or colonization with a B-lactam-resistant organism 0
Concern for necrotizing pancreatitis 0
Persistent fever or hemodynamic instability in patients already receiving broad-spectrum B-lactam 3
Severe infection in a patient who has received broad-spectrum B-lactam therapy for a 5-day course in the past 30 days 0
As recommended or approved by infectious disease consult 0
Suboptimal 5 (25%)
Severe sepsis of unknown cause 2
Healthcare-associated pneumonia 2
Severe intra-abdominal infection 1
Severe neutropenia 0
Community-acquired pneumonia with bronchiectasis or cystic fibrosis 0
Limb- or life-threatening diabetic foot or soft tissue infection 0
Urinary tract infection 0
Inappropriate 2 (10%)
Penicillin allergy 1
Treatment of a colonizing organism 0
Treatment resulting from presumed contaminated culture 0
Any indication not mentioned above 1