Characteristic |
Number of patients (%) (n = 20) |
Appropriate |
13 (65%) |
Targeted therapy supported by cultures |
10 |
Septic shock or severe infection with a history of infection in the past 6 months with a B-lactam-resistant organism |
0 |
Septic shock or severe infection with a history of multiple antibiotics given or colonization with a B-lactam-resistant organism |
0 |
Severe neutropenia with a history of multiple antibiotics given or colonization with a B-lactam-resistant organism |
0 |
Concern for necrotizing pancreatitis |
0 |
Persistent fever or hemodynamic instability in patients already receiving broad-spectrum B-lactam |
3 |
Severe infection in a patient who has received broad-spectrum B-lactam therapy for a 5-day course in the past 30 days |
0 |
As recommended or approved by infectious disease consult |
0 |
Suboptimal |
5 (25%) |
Severe sepsis of unknown cause |
2 |
Healthcare-associated pneumonia |
2 |
Severe intra-abdominal infection |
1 |
Severe neutropenia |
0 |
Community-acquired pneumonia with bronchiectasis or cystic fibrosis |
0 |
Limb- or life-threatening diabetic foot or soft tissue infection |
0 |
Urinary tract infection |
0 |
Inappropriate |
2 (10%) |
Penicillin allergy |
1 |
Treatment of a colonizing organism |
0 |
Treatment resulting from presumed contaminated culture |
0 |
Any indication not mentioned above |
1 |