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. 2022 Dec 16;12:21799. doi: 10.1038/s41598-022-24760-y

Table 1.

Minimal inhibitory concentration (MIC) and minimal bactericidal inhibitory concentration (*MBC) monomeric quaternary ammonium salts (QAS) with different counterion (Me—methylcarbonates, Ac—acetates, Br—bromides) and aliphatic chain length (C12, C14, C16).

Strain Compound
Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (*MBC) of tested compounds [µM]
MeC12 MeC14 MeC16 AcC12 AcC14 AcC16 BrC12 BrC14 BrC16
S. epidermidis ATCC 35984

320

*640

40

*40

40

*40

640

*640

160

*160

640

*640

640

*640

160

*160

640

*640

S. epidermidis B374

640

*160

80

*160

80

*160

320

*320

40

*40

40

*40

640

*640

640

* > 640

10

*10

S. epidermidis SI8

320

*640

40

*40

10

*10

640

*640

160

*160

10

*10

640

*640

160

*160

10

*10

S. aureus ATCC 6538

320

*640

80

*80

10

*10

1280

*1280

160

*160

80

*80

1280

*1280

320

*320

320

*320

S. aureus MRSA R98

640

*640

80

*80

40

*40

640

*640

160

*160

10

*10

640

*640

320

*320

320

*320

E. coli ATCC 11229

640

*640

320

*320

320

*320

1280

*1280

320

*320

80

*160

1280

*1280

 > 1280

* > 1280

640

*1280

E. coli

H64

640

*640

80

*80

80

*80

1280

*1280

160

*160

160

*320

1280

*1280

320

*320

160

*160

P. aeruginosa ATCC 27853

 > 1280

* > 1280

1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

1280

* > 1280

 > 1280

* > 1280

1280

*1280

1280

*1280

 > 1280

* > 1280

P. aeruginosa PAO1

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280

 > 1280

* > 1280