Table 4.

Numbers of genes associated with the 25 functional categories in clusters of orthologous groups (COG).

Description	COG	1	2	3	4	5	6	7
Translation	[J]	144	103	147	151	140	130	133
Rna processing and modification	[A]	0	0	0	0	0	0	0
Transcription	[K]	90	54	82	69	72	57	66
Replication, recombination and repair	[L]	144	73	133	120	127	107	79
Chromatin structure and dynamics	[B]	0	0	0	0	0	0	1
Cell cycle control, mitosis and meiosis	[D]	16	7	16	19	12	12	13
Nuclear structure	[Y]	0	0	0	0	0	0	0
Defense mechanisms	[V]	37	25	42	35	29	35	11
Signal transduction mechanisms	[T]	43	25	36	32	31	31	39
Cell wall/membrane biogenesis	[M]	206	101	212	174	126	110	93
Cell motility	[N]	14	7	13	15	14	13	18
Cytoskeleton	[Z]	1	0	1	0	0	0	0
Extracellular structures	[W]	0	0	1	0	0	0	0
Intracellular trafficking and secretion	[U]	51	26	51	46	40	39	50
Posttanslational modification, protein turnover,chaperones	[O]	79	40	73	106	57	52	61
Mobilome: prophages, transposons	[X]	0	0	0	0	0	0	0
Energy production and conversion	[C]	104	45	101	93	76	69	91
Carbohydrate transport and metabolism	[G]	129	60	137	128	84	80	72
Amino acid transport and metabolism	[E]	163	93	162	156	123	115	116
Nucleotide transport and metabolism	[F]	47	30	46	46	43	39	39
Coenzyme transport and metabolism	[H]	93	54	86	88	73	67	68
Lipid transport and metabolism	[I]	48	25	47	42	36	33	46
Inorganic ion transport and metabolism	[P]	102	80	102	96	61	57	87
Secondary metabolites biosynthesis, transport and catabolism	[Q]	26	13	22	15	11	10	34
General function prediction only	[R]	301	145	296	357	328	393	169
Function unknown	[S]	145	78	136	115	81	81	83

Akkermansia massiliensis strain Marseille-P6666 (1), Akkermansia muciniphila strain ATCC BAA-835^T (2), Candidatus Akkermansia timonensis strain Akk0196 (3), Akkermansia glycaniphila strain Pyt^T (4), “Candidatus Akkermansia intestinavium” strain ChiGjej6B6-8097^T (5), “Candidatus Akkermansia intestinigallinarum” strain 14975^T (6) and “Candidatus Mariakkermansia forsetii” strain AKK7 (7).