Table 3.

Association between cortisol awakening response (AUC^a) and behavior at age 6–7

	Extremely Preterm born				Term-born
	Reduced Modelb		Full Modelc		Reduced Modelb		Full Modelc
	β (SE)	P-value	β (SE)	P-value	β (SE)	P-value	β (SE)	P-value
WISC-IV Scores
Verbal Comprehension	0.70 (0.35)	0.05	0.67 (0.45)	0.15	0.37 (1.01)	0.72	0.34 (1.30)	0.79
Perceptual Reasoning	0.44 (0.33)	0.18	0.37 (0.44)	0.39	0.15 (0.87)	0.87	−0.05 (1.03)	0.96
Working Memory	0.28 (0.39)	0.47	0.31 (0.46)	0.50	−0.10 (0.86)	0.91	0.48 (1.00)	0.64
Processing Speed	0.50 (0.31)	0.12	0.21 (0.39)	0.58	−0.72 (0.97)	0.47	−0.44 (1.29)	0.73
NEPSY Scores
Auditory attention total	−0.33 (1.46)	0.82	−0.48 (1.81)	0.79	−0.11 (4.08)	0.98	4.58 (4.86)	0.36
Auditory attention combined	−0.01 (1.35)	0.99	−0.34 (1.69)	0.84	−1.08 (3.53)	0.76	2.36 (4.37)	0.60
Memory for name	3.23 (1.56)	0.04	3.84 (1.88)	0.04	−3.73 (3.54)	0.30	−1.70 (4.50)	0.71
Memory for names delayed	3.02 (1.52)	0.05	4.81 (1.95)	0.02	−6.39 (3.29)	0.06	−4.10 (4.40)	0.36
Conners Scores
Inattention	−0.76 (0.30)	0.01	−0.86 (0.37)	0.02	0.69 (0.76)	0.37	0.20 (0.98)	0.84
Hyperactivity/Impulsivity	−0.54 (0.31)	0.08	−0.58 (0.39)	0.14	0.62 (0.72)	0.40	0.47 (0.86)	0.59
Learning Problems	−0.92 (0.37)	0.02	−0.88 (0.46)	0.06	0.68 (1.06)	0.52	0.38 (1.32)	0.78
Executive Functioning	−0.53 (0.37)	0.15	−0.53 (0.46)	0.26	0.20 (1.02)	0.84	−0.28 (1.19)	0.81
Defiance/Aggression	−0.91 (0.39)	0.02	−0.85 (0.49)	0.09	1.64 (2.41)	0.50	3.54 (4.32)	0.42
Peer Relations	−0.51 (0.36)	0.17	−0.74 (0.44)	0.10	0.32 (1.00)	0.75	−0.19 (1.31)	0.89

^aCortisol awakening response (AUC) = increase from first awakening value to 30 minutes later

^bAdjusts for time of awakening.

^cAdjusts for time of awakening, center, sex, birthweight Z-scores, and maternal education.