Fig. 3.

Endothelial cell cytotoxicity. HPMVEC cytotoxicity induced by FFP (n = 20) considered as the gold standard versus the CCP without ARs (n = 20). HPMVEC cytotoxicity induced by negative and positive controls. Shigatoxin 145 spiked in healthy adult plasma was considered as the positive control (n = 6) and Healthy Donor Plasma-stimulated HPMVEC cells were the negative control (n = 6). Scatter dot plots represent data and the red line denotes the median of raw data. Statistical analyses were performed using one-way Anova.