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. 2021 Feb 24;79:102377. doi: 10.1016/j.janxdis.2021.102377

Table 3.

Associations of individual diagnoses of anxiety disorders with levels and changes of COVID-19-related fear, anxiety, and depressive symptoms over time as well as subjectively perceived worsening of anxiety symptoms over time (in individuals with anxiety disorders only; last column).

COVID-19- related fear (C-19-A) Depressive and anxiety symptoms (PHQ-4) Depressive symptoms (PHQ-2) Anxiety symptoms (GAD-2) Worsening of symptoms
n Observations 10,667 10,624 10,624 10,625 1,469
Coefficient b (SE) b (SE) b (SE) b (SE) b (SE)



Gender
 Male vs. female −0.160** (0.025) −0.140** (0.023) −0.057* (0.024) −0.200** (0.023) −0.009 (0.139)
 Diverse vs. fem. −0.141 (0.140) −0.036 (0.129) 0.019 (0.132) −0.094 (0.129) −0.235 (0.446)
 Diverse vs. male 0.019 (0.141) 0.104 (0.130) 0.076 (0.133) 0.106 (0.130) −0.226 (0.461)



Age 0.005** (0.001) −0.007** (0.001) −0.009** (0.001) −0.004** (0.001) −0.001 (0.005)
Other mental disorder 0.199** (0.050) 0.507** (0.046) 0.433** (0.046) 0.506** (0.046) 0.397** (0.141)
Depressive disorder 0.290** (0.040) 0.815** (0.037) 0.846** (0.038) 0.662** (0.037) 0.385** (0.124)
Agoraphobia 0.325** (0.115) 0.078 (0.107) 0.044 (0.111) 0.100 (0.108) 0.055 (0.215)
Panic disorder 0.527** (0.057) 0.460** (0.053) 0.307** (0.055) 0.541** (0.054) 0.485** (0.131)
Social anxiety disorder 0.224** (0.059) 0.498** (0.055) 0.495** (0.057) 0.428** (0.055) 0.120 (0.145)
Generalized anxiety disorder 0.627** (0.052) 0.614** (0.049) 0.376** (0.050) 0.753** (0.049) 0.853** (0.133)
Other anxiety disorders 0.143 (0.084) 0.342** (0.078) 0.343** (0.080) 0.291** (0.079) −0.214 (0.185)
Symptom change −0.257** (0.007) −0.075** (0.008) −0.041** (0.008) −0.095** (0.008) −0.235* (0.104)
Symptom change * Agoraphobia −0.076 (0.073) 0.085 (0.076) 0.084 (0.083) 0.054 (0.080) 0.059 (0.168)
Symptom change * Panic disorder −0.023 (0.033) −0.017 (0.035) −0.025 (0.038) −0.008 (0.037) 0.110 (0.092)
Symptom change * Social anxiety disorder −0.009 (0.032) −0.007 (0.034) −0.023 (0.037) 0.012 (0.036) −0.028 (0.097)
Symptom change * Generalized anxiety disorder −0.116** (0.028) −0.079** (0.029) −0.047 (0.032) −0.093** (0.031) −0.202* (0.095)
Symptom change * other anxiety disorder −0.037 (0.041) −0.097* (0.044) −0.099* (0.047) −0.088 (0.046) 0.001 (0.120)

Note. b = coefficient from multilevel mixed-effect models (the values of the variable worsening were computed in a separate model with only the participants which stated to have a anxiety disorders, because only those answered the item). Standard errors are in parenthesis. Significance levels: ** p < 0.01, * p < 0.05.