Skip to main content
. 2022 Dec 5;18:100512. doi: 10.1016/j.mtbio.2022.100512

Fig. 8.

Fig. 8

PEVS restored mitochondrial membrane potential homeostasis and mitochondrial function. Scale bar ​= ​20 ​μm. (A) Protective effect of PEVs was evaluated by MitoTracker Green. (B) Quantification of fluorescence intensities according to (A). (C) Detection of mitochondrial membrane potentials in four groups of cells by JC-1 fluorescence probe. Scale bar ​= ​50 ​μm. (D) Quantification of fluorescence intensities according to (C). (E) Detection of lactic acid content in supernatant of NP cells culture medium. (F) ATP levels of NP cells was detected. (G) Transmission electron microscopy (TEM) images of mitochondria in NP cells. Scale bar ​= ​0.5 ​μm. Significance between four groups was calculated using one-way ANOVA with Tukey's post-hoc test. Data are presented as mean ​± ​SD (n ​= ​4). (Scale bars are listed above; ∗: P ​< ​0.05, ∗∗: P ​< ​0.01, ∗∗∗: P ​< ​0.005, and ∗∗∗∗: P ​< ​0.001).