TABLE 2.

Infertility diagnoses and in vitro fertilization treatment parameters by plurality

Plurality at birth	Singletons				Twins				Triplets+
Oocyte source- embryo state	Autologous- fresh	Autologous- thawed	Donor- fresh	Donor- thawed	Autologous- fresh	Autologous- thawed	Donor- fresh	Donor- thawed	Autologous- fresh	Autologous- thawed	Donor- fresh	Donor- thawed
N, pregnancies	56,037	16,997	8129	3574	22,858	4686	4921	1041	1359	281	168	55
Prior IVF
Women with prior cycles, %	54.3	91.7	66.8	89.9	52.1	91.3	68.1	87.2	61.1	92.9	71.3	81.8
Prior cycles, mean (SD)	1.6 (2.2)	2.7 (2.6)	2.5 (2.9)	3.7 (3.5)	1.5 (2.1)	2.4 (2.2)	2.6 (2.9)	3.3 (3.1)	1.8 (2.2)	2.7 (2.3)	2.6 (3.1)	3.4 (3.3)
Diagnoses male factor, %	40.5	40.0	19.7	19.9	42.2	40.1	21.0	19.9	45.3	42.4	29.1	20.0
Endometriosis	12.0	11.7	6.6	6.9	12.9	11.9	6.6	7.4	13.6	13.9	7.2	1.8
Ovulation disorders	15.8	20.1	3.2	4.4	18.2	21.7	4.4	4.5	18.1	24.3	3.2	5.5
Diminished ovarian reserve	16.3	10.6	78.2	77.4	11.2	8.2	77.9	75.8	11.8	6.4	72.5	79.4
Tubal factors	16.1	16.7	6.9	7.8	16.7	17.6	7.6	8.2	19.4	24.3	11.1	9.7
Uterine factors	4.3	4.5	4.8	5.7	3.9	4.1	4.7	5.4	3.8	3.1	3.8	3.6
Other factors	11.8	12.2	16.4	16.6	10.7	11.6	15.5	17.3	10.0	9.6	10.0	12.7
Unexplained	13.7	13.0	3.6	2.9	13.8	13.1	3.6	3.5	12.5	8.6	5.4	1.8
Embryos transferred, %
1	12.2	24.1	15.3	21.8	0.6	1.9	0.3	1.4	0.3	0.7	0.0	0.0
2	53.1	51.0	70.8	53.4	65.3	63.1	83.5	63.8	26.8	19.8	43.7	14.5
>2	34.8	24.9	14.0	24.8	34.1	35.0	16.1	34.7	73.0	79.5	56.3	85.5
Fetal heartbeats at 6 wk, %
1	92.0	94.3	89.2	94.1	0.9	1.0	0.5	1.5	0.4	1.3	1.8	0.0
2	7.1	5.2	9.5	5.4	93.5	93.5	95.4	93.6	4.4	1.4	4.6	4.8
>2	0.9	0.5	1.2	0.6	5.6	5.5	4.1	4.9	95.1	97.2	93.6	95.2

IVF, in vitro fertilization.

Luke et al. Risk of severe maternal morbidity. Am J Obstet Gynecol 2019.