. Author manuscript; available in PMC: 2022 Dec 17.

Published in final edited form as: Am J Obstet Gynecol. 2018 Oct 12;220(2):195.e1–195.e12. doi: 10.1016/j.ajog.2018.10.012

TABLE 5.

Risks of severe maternal morbidity among women with prior birth by maternal fertility

	Admission to intensive care		Blood transfusion				Unplanned hysterectomy
Mode of delivery	Cesarean		Vaginal		Cesarean		Cesarean
N, Pregnancies	250,345		452,953		250,345		250,345
Outcomes, %	720	0.29%	451	0.10%	937	0.37%	286	0.11%
	AOR	95% CI	AOR	95% CI	AOR	95% CI	AOR	95% CI
Fertile	1.00	Reference	1.00	Reference	1.00	Reference	1.00	Reference
Subfertile	0.58	0.25–1.35	2.91^a	1.38–6.15^a	1.04	0.58–1.84	0.85	0.27–2.71
IVF autologous-fresh	0.84	0.62–1.15	1.93^a	1.23–3.01^a	1.06	0.82–1.37	0.79	0.48–1.33
IVF autologous-thawed	1.37	0.94–1.99	2.99^a	1.78–5.02^a	1.74^a	1.29–2.33^a	2.31^a	1.43–3.71^a
IVF donor-fresh	1.24	0.78–1.97	5.13^a	2.39–11.02^a	1.62^a	1.07–2.45^a	1.38	0.62–3.06
IVF donor-thawed	0.84	0.39–1.82	5.20^a	1.83–14.82^a	1.64	0.94–2.87	2.45^a	1.06–5.67^a

Models adjusted for maternal fertility status, age, parity, race and ethnicity, hypertension and diabetes (pregestational and gestational), plurality at birth, length of gestation, mode of delivery, and prior mode of delivery, as well as state and year of birth and infant sex.

AOR, adjusted odds ratio; CI, confidence interval; IVF, in vitro fertilization.

Significantly increased compared to reference group.

Luke et al. Risk of severe maternal morbidity. Am J Obstet Gynecol 2019.