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Validation of gene expression levels of VNNs in datasets. A, C VNNs in healthy (n = 64) and periodontitis (n = 183) sites in dataset GSE10334 were presented. B, D VNNs in healthy (n = 69) and periodontitis (n = 241) sites in dataset GSE16134 were presented. Z-score was analyzed and enrolled in the establishment of heatmaps. Significance was defined in the figure as **** p < 0.0001
