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. 2022 Dec 16;23:836. doi: 10.1186/s12864-022-09073-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — The distinct miRNAs expression profiles between groups. a The heat map represents hierarchical clustering for DE miRNAs between the SD group and Ctrl group; b The heat map represents hierarchical clustering for DE miRNAs in the ALI group compared with the Ctrl group; c The heat map represents hierarchical clustering for DE miRNAs in the SD + ALI group compared with the ALI group. d The volcano plots for DE miRNAs in the SD group compared with Ctrl group; e The volcano plots for DE miRNAs in the ALI group compared with the Ctrl group; f The volcano plots for DE miRNAs in the SD + ALI group compared with the ALI group. Up-regulated expression was indicated as “red”, and down-regulated expression was indicated as “green”