Table 4.
The pathways with the highest magnitude SVM weights from CPE for each experiment and time.
| Experiment | Time (h) | Reactome ID | Pathway name | Genes | Probes |
|---|---|---|---|---|---|
| 4 studies | 1-8 | R-HSA-74713 | IRS activation | 5 | 10 |
| 4 studies | 9-16 | R-HSA-74713 | IRS activation | 5 | 10 |
| 4 studies | 17-24 | R-HSA-2179392 | EGFR Transactivation by Gastrin | 9 | 22 |
| 4 studies | 25-32 | R-HSA-3595177 | Defective CHSY1 causes TPBS | 8 | 21 |
| 6 studies | 1-8 | R-HSA-2485179 | Activation of the phototransduction cascade | 11 | 20 |
| 6 studies | 9-16 | R-HSA-8939242 | RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | 8 | 25 |
| 6 studies | 17-24 | R-HSA-9694631 | Maturation of nucleoprotein | 16 | 27 |
| 6 studies | 25-32 | R-HSA-5218921 | VEGFR2 mediated cell proliferation | 21 | 53 |
CPE configurations are pre-computed, directed edges with PageRank centrality. All experiments apply LIMMA using subject identifier to the data.