TABLE 1.

Mean (standard deviation) and significance level of blood–brain barrier (BBB) Ktrans histogram peak height and peak position for each region‐of‐interest (ROI) for APOEe3 and APOEe4 carriers

	APOEe3(19)	APOEe4(17)	p	d	APOEe3(19)	APOEe4(17)	p	d
	Peak	Height			Peak Position
Left hippocampus	4.66 (1.8)	4.41 (1.5)	.704	0.15	1.21 (1.2)	1.35 (0.7)	.791	0.14
Right hippocampus	3.65 (2.7)	4.06 (4.4)	.741	0.11	1.16 (0.9)	1.29 (0.9)	.738	0.14
Left WM ACC	4.00 (2.3)	3.43 (1.7)	.535	0.28*	1.00 (0.6)	1.02 (0.6)	.789	0.03
Right WM ACC	3.98 (1.8)	4.16 (2.1)	.468	0.09	0.77 (0.9)	0.78 (0.6)	.629	0.01
Left anterior cortex	9.95 (9.9)	7.41 (3.1)	.442	0.35*	0.78 (0.6)	0.68 (0.6)	.302	0.16
Right anterior cortex	4.37 (1.6)	4.20 (2.2)	.922	0.09	0.52 (0.5)	0.56 (0.4)	.901	0.09
Parahippocampal gyrus anterior	2.43 (2.0)	2.11 (2.0)	.648	0.16	1.90 (1.7)	1.85 (1.3)	.951	0.03
Parahippocampal gyrus posterior	2.78 (1.3)	3.20 (1.4)	.427	0.31*	1.44 (1.1)	1.72 (1.3)	.251	0.23*
Subcortical probe Left hippocampus	3.44 (1.5)	3.39 (1.9)	.974	0.03	1.16 (1.0)	1.29 (0.8)	.646	0.14
Subcortical probe right hippocampus	3.55 (1.6)	3.56 (1.1)	.842	0.01	1.18 (1.0)	1.29 (0.9)	.389	0.12

Note: Peak position is in unit (×10⁻³ min⁻¹).

Abbreviations: d, Cohen's effect size; WM ACC, white matter anterior cingulate cortex.

Significant (p < .05).

^*Small effect size detected.