Fig. 12.

(a) Schematic of the LFA biosensor for simultaneous detection of two nucleic acids. The strip is composed of two test lines and one control line. (b) (i) KSHV DNA-AuNP complexes were captured by the probe KSHV DNAs on the first test line, (ii) BA DNA-AuNPs complexes were captured by the probe BA DNAs on the second test line, and (iii) excess KSHV and BA detection DNAs attached to AuNPs were captured by control DNAs through T20-A20 hybridization on the third control line. (c) Corresponding DNA hybridizations for two test lines (i and ii) and one control line (iii). Reprinted with permission from Ref. [111]. Copyright 2017 American Chemical Society.