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. 2022 Dec 17;12:21820. doi: 10.1038/s41598-022-24276-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Probability density functions of the T1 values (a), T2 values (b), the norm of T1 and T2 values –normT1T2- (c), and the norm of the logarithm of T1 and T2 values –normlog- (d) for all the patients showing T1w-enhancement (solid line) and for all the patients without T1w-enhancement (dashed line) for each region of interest (ROI) (Blue→normal white matter -nWM-, Red→perilesional area –PER-, Yellow→T2w-hyperintensity -T2h-, Purple→T1w-enhancement -T1e-, Green—> Abnormal tissue.