TABLE 2.
Histological characteristics of lesions identified by 10.5 T MRI
| Specimen | Joint affected | Site | Maximum widtha (mm) | Maximum thicknessb (mm) | Histologic features | Diagnosis |
|---|---|---|---|---|---|---|
| 4-week | Elbow | Humerus—trochlea | 2.5 | 1.5 |
Epiphyseal chondronecrosis
Necrotic vascular profiles |
OCL |
| 8-week | Elbow | Humerus—trochlea | 3.3 | 1.5 |
Epiphyseal chondronecrosis
Necrotic vascular profiles |
OCL |
| 12-week | Elbow | Humerus—trochlea | 6.5 | 2 |
Epiphyseal chondronecrosis Necrotic vascular profiles Delay of endochondral ossification Cleft formation without displacement Bone resorption, Myelofibrosis |
OCL, OCM |
| 12-week | Knee/stifle | Femur—medial condyle | 6.5 | 5.4 |
Epiphyseal chondronecrosis
Necrotic vascular profiles Delay of endochondral ossification |
OCM |
Note: Italics denote diagnostic features.
Abbreviations: MRI, magnetic resonance imaging; OCL, osteochondrosis latens; OCM, osteochondrosis manifesta.
a
Width of lesions were measured in the serial histological section that captured the lesions at their largest point and refers to the greatest extent of the lesion as measured in the plane approximately parallel to the underlying chondrosseous junction.
b
Thickness refers to the maximum thickness of affected cartilage as measured in the plane perpendicular to the chondrosseous junction.