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. 2021 Mar 26;41:127990. doi: 10.1016/j.bmcl.2021.127990

Table 2.

Inhibition of SARS-CoV-2 Mpro by hit compounds.

Compound Structure Inhibition (%)b
CP-2 graphic file with name fx1_lrg.gif n.d.
CP-3 graphic file with name fx2_lrg.gif 6.54 ± 3.60
CP-5 graphic file with name fx3_lrg.gif 1.16 ± 6.12
CP-7 graphic file with name fx4_lrg.gif 16.57 ± 3.12
CP-8 graphic file with name fx5_lrg.gif 6.29 ± 3.32
CP-9 graphic file with name fx6_lrg.gif 9.38 ± 6.75
CP-10 graphic file with name fx7_lrg.gif 7.54 ± 1.30
CP-11 graphic file with name fx8_lrg.gif n.d.a
CP-12 graphic file with name fx9_lrg.gif 7.42 ± 2.39
CP-13 graphic file with name fx10_lrg.gif 45.71 ± 8.98
CP-14 graphic file with name fx11_lrg.gif 8.84 ± 1.45
CP-16 graphic file with name fx12_lrg.gif 5.21 ± 1.07
CP-20 graphic file with name fx13_lrg.gif n.d.
CP-22 graphic file with name fx14_lrg.gif 8.23 ± 3.77
CP-23 graphic file with name fx15_lrg.gif 11.11 ± 0.90
CP-24 graphic file with name fx16_lrg.gif 5.26 ± 4.51
CP-25 graphic file with name fx17_lrg.gif 35.64 ± 10.24
CP-26 graphic file with name fx18_lrg.gif 14.34 ± 9.23
CP-27 graphic file with name fx19_lrg.gif 76.63 ± 55.40a
CP-28 graphic file with name fx20_lrg.gif 6.87 ± 3.14
a

Autofluorescent compound.

b

Values are reported as the means ± SD of three measurements.